Registration Dossier
Registration Dossier
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EC number: 201-854-9 | CAS number: 88-73-3
Toxicity to microorganisms
Administrative data
- Endpoint:
- toxicity to microorganisms
- Type of information:
- experimental study
- Adequacy of study:
- other information
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: Standardized procedure. Basic data given.
Data source
Referenceopen allclose all
- Reference Type:
- publication
- Title:
- QSAR study of the toxicity of nitrobenzene derivatives towards Daphnia magna, Chlorella pyrenoidosa and Photobacterium phosphoreum.
- Author:
- Deneer JW, van Leeuwen CJ, Seinen W, Maas-Diepeveen JL, Hermens JLM
- Year:
- 1 989
- Bibliographic source:
- Aquatic Toxicology 15: 83-98
- Reference Type:
- other: operating manual
- Title:
- Microtox system operating manual 015555879.
- Author:
- Beckman Instruments Inc.
- Year:
- 1 982
- Bibliographic source:
- Beckman Instruments Inc., Carlsbad
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 1 986
Materials and methods
- Principles of method if other than guideline:
- Microtox test: carried out as described in the Beckman Instruments Manual (1982)
- GLP compliance:
- not specified
Test material
- Reference substance name:
- 1-chloro-2-nitrobenzene
- EC Number:
- 201-854-9
- EC Name:
- 1-chloro-2-nitrobenzene
- Cas Number:
- 88-73-3
- Molecular formula:
- C6H4ClNO2
- IUPAC Name:
- 1-chloro-2-nitrobenzene
- Details on test material:
- - Name of test material (as cited in study report): 2-Chloronitrobenzene
- Analytical purity: no data
Constituent 1
Sampling and analysis
- Analytical monitoring:
- no
Test organisms
- Test organisms (species):
- Photobacterium phosphoreum
Study design
- Limit test:
- no
- Total exposure duration:
- 15 min
Test conditions
- Nominal and measured concentrations:
- spacing factor of nominal test substance concentrations: 3.2
Results and discussion
Effect concentrations
- Duration:
- 15 min
- Dose descriptor:
- EC50
- Effect conc.:
- 4.54 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- other: reduction of bioluminescence
Any other information on results incl. tables
result reported as log EC50 = 1.46 µmol/l
Applicant's summary and conclusion
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
