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Environmental fate & pathways

Biodegradation in water: screening tests

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Description of key information

n-Octylamine is readily biodegradable.

Key value for chemical safety assessment

Biodegradation in water:
readily biodegradable

Additional information

Within the reliable key study (pre-guideline, comparable to OECD TG 301-C, i.e. MITI-I), biodegradation of n-octylamine (test substance: HCl salt of octylamine, see read-across document IUCLIDsection 13) was examined in a test for ready biodegradability. The BOD accounted for approx. 65% of the ThOD (theoretical oxygen demand) after 5 days, and for approx. 73% after 12 days of culture. N-octylamine is therefore considered to be readily biodegradable fulfilling the 10-day window requirement (Yoshimura et al., 1980).

This is supported by another reliable study demonstrating ready biodegradability of octylamine (BASF AG, 1997; Report No. 96/0345/21/1): the study was performed according to OECD 301A, domestic activated sludge was used as inoculum. The degradation reached 99% after 11 d, the 10 -d window was kept.

A third supporting study on inherent biodegradability is available (Zahn-Wellens test, pre-guideline, equivalent to OECD 302B), again demonstrating rapid biodegradability of n-octylamine: non-adapted activated sludge of a sewage treatment plant served as inoculum. Test substance was incubated for 20 days at 22°C. After 20 days n-octylamine was degraded by >77%. It  isconcluded that the criteria for inherent biodegradability were met  (Hoechst, 1980).