Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Endpoint:
in vivo mammalian somatic cell study: cytogenicity / bone marrow chromosome aberration
Remarks:
Type of genotoxicity: chromosome aberration
Adequacy of study:
other information

Data source

Reference
Reference Type:
other: Body responsible for the test
Title:
Unnamed

Materials and methods

Test guideline
Qualifier:
according to guideline
Guideline:
other: OECD 474 (1997)
GLP compliance:
yes
Type of assay:
micronucleus assay

Test material

Details on test material:
Batch no : A4305 05008

Test animals

Species:
other: mus, CD-1

Administration / exposure

Route of administration:
inhalation
Vehicle:
Edenol (epoxised soya bean oil).

Results and discussion

Test results
Toxicity:
yes
Remarks:
Doses producing toxicity: Toxic signs at the highest tested concentration of 600 ppm.
Additional information on results:
Observations:
No lethal effects; no cytotoxicity (PCE/NCE).

Applicant's summary and conclusion

Conclusions:
Interpretation of results: negative