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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

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Ecotoxicological information

Endpoint summary

Administrative data

Description of key information

Additional information

Read across from toxicity study to aquatic invertebrates of pivalic acid (CAS 75-98-9), which is the hydrolysis product of trimethylacetic anhydride, is possible. Trimethylacetic anhydride ist not stable in water and hydrolyses within hours (For details see chapter 5.1.2).

6.1.3 Short-term toxicity to aquatic invertebrates: The acute toxicity of pivalic acid (CAS 75-98-9) to Daphnia magna was investigated in a static GLP study following OECD 202. After 48 hours of exposure the EC50 value was 87.4 mg/L (pH not adjusted). In the test system in which the pH-value was adjusted to the pH value ± 0.3 of the control group no swimming inhibition (EC0) was observed in the test system (101 mg/L). The results relate to the arithmetic mean of the measured concentration.

6.1.5 Toxicity to aquatic algae and cyanobacteria: The toxicity of pivalic acid (CAS 75-98-9) to algae was investigated in a static GLP study following OECD 201. During 72 hours of exposure an ErC50 of 66.0 mg/L and a NOEC of 46.5 mg/L were detected in the test system without pH-adjustment. In the test system in which the pH-value was adjusted to the pH value ± 0.3 of the control group an ErC50 of higher than 96.6 and a NOEC of 96.6 mg/L were received. The results relate to the arithmetic mean of the measured concentration.