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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Ecotoxicological information

Toxicity to aquatic algae and cyanobacteria

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Administrative data

Link to relevant study record(s)

Description of key information

The 72-h ErC50 and NOErC values are 0.67 mg/L and 0.15 mg/L, respectively in freshwater algae (P. subcapitata).

Key value for chemical safety assessment

EC50 for freshwater algae:
0.67 mg/L
EC10 or NOEC for freshwater algae:
0.15 mg/L

Additional information

A GLP compliant study was performed, according to OECD guideline 201, to determine the effect of tetramethyl bisphenol A (TMBPA) (nominal test concentrations 0.010, 0.026, 0.064, 0.16, 0.40 and 1.0 mg/L) on the growth of the freshwater green alga Pseudokirchneriella subcapitata.  Exposure of algae to TMBPA for 72 hours resulted in median effective concentrations (EC50) of 0.37 and 0.67 mg/L for cell yield and average growth rate, respectively. The 72 hour no observed effect concentration (NOEC) was 0.15 mg/L for both yield and average growth rate.