Registration Dossier
Registration Dossier
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EC number: 201-757-1 | CAS number: 87-61-6
Additional toxicological data
Administrative data
- Endpoint:
- additional toxicological information
- Type of information:
- experimental study
- Adequacy of study:
- other information
- Reliability:
- 3 (not reliable)
- Rationale for reliability incl. deficiencies:
- other: Documentation insufficient for assessment: mixture of 18 toxicants: With respect to 1,2,3 trichlorobenzene alone the publication provides no information.
Data source
Reference
- Title:
- No information
- Author:
- Foster WG et al. (2004), Mammary gland morphology in Sprague-Dawley rats following treatmet with an organochlorine Mixture in utero and neonatatal genestein. Toxicol. Sci. 77, 91-100
Materials and methods
- Type of study / information:
- Type: other
- Principles of method if other than guideline:
- Pregnant female rats were exposed in utero once a day from day 9- 16 of gestation to a mixture of 18 toxicants (1x the acceptable daily intake) to examine the effect on mammary gland histology. One component of the mixture was 1,2,3-trichlorobenzene. Only mild histological changes were found in mammary glands of the rats.
- GLP compliance:
- not specified
Test material
- Reference substance name:
- 1,2,3-trichlorobenzene
- EC Number:
- 201-757-1
- EC Name:
- 1,2,3-trichlorobenzene
- Cas Number:
- 87-61-6
- Molecular formula:
- C6H3Cl3
- IUPAC Name:
- 1,2,3-trichlorobenzene
Constituent 1
Results and discussion
Applicant's summary and conclusion
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