Registration Dossier
Registration Dossier
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EC number: 221-346-0 | CAS number: 3072-84-2
Water solubility
Administrative data
Link to relevant study record(s)
- Endpoint:
- water solubility
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 13/04/2012-07/06/2012
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Reason / purpose for cross-reference:
- reference to same study
- Qualifier:
- according to guideline
- Guideline:
- EPA OPPTS 830.7840 (Water Solubility)
- Qualifier:
- according to guideline
- Guideline:
- EPA OPPTS 830.7860 (Water Solubility Generator Column Method)
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 105 (Water Solubility)
- GLP compliance:
- yes
- Type of method:
- column elution method
- Key result
- Water solubility:
- 26.4 µg/L
- Conc. based on:
- test mat.
- Temp.:
- 20 °C
- pH:
- > 6.47 - < 7.64
- Remarks on result:
- other:
- Remarks:
- pH of reagent water: 6.47 and an aqueous sample: 7.64
- Details on results:
- Under the instrumental conditions presented, the mean measured reagent water solubility of F-2200 HM, based on the primary component, at 20°C was 25.8 ± 2.0 μg/L (CV = 7.7%, N = 5) at a flow rate of approximately 1.0 mL/min and was 27.0 ± 0.43 μg/L (CV = 1.6%, N = 5) at a flow rate of approximately 0.5 mL/min. The mean measured F-2200 HM concentration as a function of flow-rate differed by 4.4%, which was well within the ±30% test criterion. The overall mean measured water solubility of F-2200 HM, based on the primary component, at 20°C was 26.4 ± 1.5 μg/L (CV = 5.7%, N = 10).
The mean measured reagent water solubility of F-2200 HM, based on the secondary component, at 20°C was less than the LOQ (20.0 μg/L) at both flow rates. The overall mean measured water solubility of F-2200 HM, based on the secondary component, at 20°C was less than the LOQ (20.0 μg/L).
The pH was measured for an aqueous sample collected at a flow rate of 1.0 mL/min. The measured pH of reagent water and an aqueous sample was 6.47 and 7.64, respectively. - Conclusions:
- The water solubility of F-2200 HM, based on the primary component, in reagent water at 20oC using the column elution method was determined to be 26.4 ± 1.5 μg/L.
- Executive summary:
The water solubility of F-2200 HM was meaured at 20oC by using the column elution method and was determined to be 26.4 ± 1.5 μg/L.
Reference
Description of key information
The water solubility of F-2200, based on the primary component, in reagent water at 20°C using the column elution method was 26.4 μg/L.
Key value for chemical safety assessment
- Water solubility:
- 26.4 µg/L
- at the temperature of:
- 20 °C
Additional information
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