Registration Dossier
Registration Dossier
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
REACH
(3R,4S,5S,6R,7R,9R,10E,11S,12R,13S,14R)-6-[(2S,3R,4S,6R)-4-(dimethylamino)-6-methyl-3-trimethylsilyloxyoxan-2-yl]oxy-10-(2-ethoxypropan-2-yloxyimino)-14-ethyl-12,13-dihydroxy-7-methoxy-4-[(2R,4R,5S,6S)-4-methoxy-4,6-dimethyl-5-trimethylsilyloxyoxan-2-yl]oxy-3,5,7,9,11,13-hexamethyl-oxacyclotetradecan-2-one
EC number: 805-486-5 | CAS number: 119665-62-2
Guidance on Safe Use
Guidance on Safe Use
Administrative data
First-aid measures
In all cases of doubt, or when symptoms persist, seek medical attention.
In case of inhalation: remove from area to fresh air. If breathing becomes difficult, give oxygen. Get medical attention.
In case of skin contact: remove contaminated clothing. Wash skin with water, using soap if available.
In case of eye contact: immediately flush eyes with plenty of water. Consult a physician.
In case of ingestion: Rinse mouth with 2-4 cup of water or milk if concious. Induce vomiting. Get medical advice/attention if you feel unwell.
The product is not classified as harmful to human health effect.
If skin irritation or rash occurs, get medical advice/attention.
In case of inhalation: remove from area to fresh air. If breathing becomes difficult, give oxygen. Get medical attention.
In case of skin contact: remove contaminated clothing. Wash skin with water, using soap if available.
In case of eye contact: immediately flush eyes with plenty of water. Consult a physician.
In case of ingestion: Rinse mouth with 2-4 cup of water or milk if concious. Induce vomiting. Get medical advice/attention if you feel unwell.
The product is not classified as harmful to human health effect.
If skin irritation or rash occurs, get medical advice/attention.
Fire-fighting measures
Extinguishing media:
Suitable extinguishing media: use water spray, dry chemical, carbon dioxide, or chemical foam.
Unsuitable extiguishing media: Not available
In case of fire, the following can be released: carbon oxides, nitrogen oxides and other toxic fumes.
Advice for fire-fighters: As in any fire, wear self-contained breathing apparatus pressure-demand.MSHA/NIOSH (approved or equivalent) and full.
Suitable extinguishing media: use water spray, dry chemical, carbon dioxide, or chemical foam.
Unsuitable extiguishing media: Not available
In case of fire, the following can be released: carbon oxides, nitrogen oxides and other toxic fumes.
Advice for fire-fighters: As in any fire, wear self-contained breathing apparatus pressure-demand.MSHA/NIOSH (approved or equivalent) and full.
Accidental release measures
For non-emergency personnel: Provide adequate ventilation. Avoid inhalation of vapour or dust. Avoid skin and eye contact. Wear protective gloves/protective clothing/eye protective/face protection.
For emergency responders:Wear an appropiate NIOSH/MSHA approved respirator if mist, vapor or dust is generated.
Environmental precautions: Do not allow material to be released to the environment without proper gevermmnetal permits.
Methods for containment and cleaning up: Clean up spills immediately, using the appropriate protective equipment. Sweep up, then place into a suitable container disposal. Avoid generating dusty conditions. Provide ventilation.
For emergency responders:Wear an appropiate NIOSH/MSHA approved respirator if mist, vapor or dust is generated.
Environmental precautions: Do not allow material to be released to the environment without proper gevermmnetal permits.
Methods for containment and cleaning up: Clean up spills immediately, using the appropriate protective equipment. Sweep up, then place into a suitable container disposal. Avoid generating dusty conditions. Provide ventilation.
Handling and storage
Protective measures: Wash thoroughly after handling. Wash contaminant clothes. Avoid contact with skin and eyes.Avoid ingestion and inhalation. Provide appropriate exhaust ventilatiob at places where dust is formed.
Advice on general occupational hygiene: Do not eat, drink and smoke in work areas. Wash hands after use. Remove contaminated clothing and protective equipment before entering eating areas.
Conditions for safe storage, including incompatibilities: Store in a cool, dry, well-ventilated area away from incompatible substances.
Handle the substance under strictly controlled conditions according to Article 18(4) of REACH Regulation. Rigorous containment should be achieved.
Advice on general occupational hygiene: Do not eat, drink and smoke in work areas. Wash hands after use. Remove contaminated clothing and protective equipment before entering eating areas.
Conditions for safe storage, including incompatibilities: Store in a cool, dry, well-ventilated area away from incompatible substances.
Handle the substance under strictly controlled conditions according to Article 18(4) of REACH Regulation. Rigorous containment should be achieved.
Transport information
Land transport (UN RTDG/ADR/RID)
- UN number:
- Not regulated
Shipping information
- Proper shipping name and description:
- Not regulated
- Chemical name:
- Not regulated
- Language:
- English
- Labels:
- Not regulated
SpecialProvisionsopen allclose all
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Remarksopen allclose all
Marine transport (UN RTDG/IMDG)
- UN number:
- Not regulated
Shipping information
- Proper shipping name and description:
- Not regulated
- Chemical name:
- Not regulated
- Labels:
- Not regulated
Remarksopen allclose all
Air transport (UN RTDG/ICAO/IATA)
- UN number:
- Not regulated
Shipping information
- Proper shipping name and description:
- Not regulated
- Chemical name:
- Not regulated
- Labels:
- Not regulated
Remarksopen allclose all
SpecialProvisionsopen allclose all
Exposure controls / personal protection
Control parameters: Not available
Exposure controls:
- Appropriate engineering controls: Handle in accordance with good industrial hygiene and safety practice. Wash hands during breacks and at the end of the work. Avoid contact with eyes and skin.
Individual protection measures, such as personal protective equipment:
- Eye/face protection: Wear chemical safety glasses
hand protection: Wear appropriate protective gloves to prevent skin exposure.
- Body protection: Wear appropriate normal working clothing.
Respiratory protection: Avoid breathing dust. In case of dust contact, wear suiteable respiratory equipment. Wear air respirator if necessary.
- Thermak hazards: Wear suitable protective clothing to prevent heat.
Environmental exposure controls: Avoid discharge into the environment. According to local regulations, Federal and official regulations.
The substance is used under strictly controlled conditions during its whole lifecycle as described under Article 18 (4) and Section 2.1 of the Guidance for Intermediates. The substance should be rigorously contained by technical means during its whole lifecycle and procedural and control technologies should be in place in order to minimize emissions and any resulting exposure as described under Article 18(4). Personal protective equipment (PPE) should be used in cases of accidents and where waste is generated. The PPE may be also used as a good practice.
Exposure controls:
- Appropriate engineering controls: Handle in accordance with good industrial hygiene and safety practice. Wash hands during breacks and at the end of the work. Avoid contact with eyes and skin.
Individual protection measures, such as personal protective equipment:
- Eye/face protection: Wear chemical safety glasses
hand protection: Wear appropriate protective gloves to prevent skin exposure.
- Body protection: Wear appropriate normal working clothing.
Respiratory protection: Avoid breathing dust. In case of dust contact, wear suiteable respiratory equipment. Wear air respirator if necessary.
- Thermak hazards: Wear suitable protective clothing to prevent heat.
Environmental exposure controls: Avoid discharge into the environment. According to local regulations, Federal and official regulations.
The substance is used under strictly controlled conditions during its whole lifecycle as described under Article 18 (4) and Section 2.1 of the Guidance for Intermediates. The substance should be rigorously contained by technical means during its whole lifecycle and procedural and control technologies should be in place in order to minimize emissions and any resulting exposure as described under Article 18(4). Personal protective equipment (PPE) should be used in cases of accidents and where waste is generated. The PPE may be also used as a good practice.
Stability and reactivity
Reactivity: The substance is stable under normal storage and handling conditions.
Chemical stability: Stable at room temperature in closed containers under normal storage and handling conditions.
Posibility of hazardous reactions: No dangerous reactions known.
Conditions to avoid: Incompatible materials. Dust genreation, excess heat, exposure to moist air or water.
Incompatible materials: Strong oxidizing agents.
Hazardous decomposition products: Descomposition products may include the following materials: carbon oxides, nitrogen oxides and other toxic fumes.
Chemical stability: Stable at room temperature in closed containers under normal storage and handling conditions.
Posibility of hazardous reactions: No dangerous reactions known.
Conditions to avoid: Incompatible materials. Dust genreation, excess heat, exposure to moist air or water.
Incompatible materials: Strong oxidizing agents.
Hazardous decomposition products: Descomposition products may include the following materials: carbon oxides, nitrogen oxides and other toxic fumes.
Disposal considerations
Waste treatment methods: Chemical waste generators must determine whether a discarded chemical is classified as hazardous waste. Additionally, waste generators must consult state and local hazardous waste regulations to ensure complete and accurate classification.
Product/Packaging disposal: If empty retains product residues, all label precautions must be observed. Return for reuse or dispose according to national or local regulations.
Product/Packaging disposal: If empty retains product residues, all label precautions must be observed. Return for reuse or dispose according to national or local regulations.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
