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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Endpoint:
relative density
Type of information:
experimental study
Adequacy of study:
key study
Study period:
05 Oct 2020
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2020
Report date:
2020

Materials and methods

Test guidelineopen allclose all
Qualifier:
according to guideline
Guideline:
OECD Guideline 109 (Density of Liquids and Solids)
Version / remarks:
2012
Deviations:
no
Qualifier:
according to guideline
Guideline:
EU Method A.3 (Relative Density)
Deviations:
no
Qualifier:
according to guideline
Guideline:
EPA OPPTS 830.7300 (Density / Relative Density / Bulk Density)
Version / remarks:
2002
Deviations:
no
GLP compliance:
yes (incl. QA statement)
Type of method:
air comparison pycnometer (for solids)

Test material

Constituent 1
Chemical structure
Reference substance name:
(2S,4R)-1-[(tert-butoxy)carbonyl]-4-hydroxypyrrolidine-2-carboxylic acid
EC Number:
604-011-7
Cas Number:
13726-69-7
Molecular formula:
C10H17NO5
IUPAC Name:
(2S,4R)-1-[(tert-butoxy)carbonyl]-4-hydroxypyrrolidine-2-carboxylic acid
Test material form:
solid: particulate/powder

Results and discussion

Density
Key result
Type:
relative density
Density:
1.222
Temp.:
20 °C

Any other information on results incl. tables

Results of the measurement of the density of the test item

temperature (°C) amount of test item (g) average sample volume (cm³) density (g/cm³)
20 7.372 6.029 1.223
20 7.465 6.117 1.220

The mean density of the test item at 20 °C is 1.222 g/cm³. The relative density is 1.222.

Applicant's summary and conclusion

Conclusions:
According to OECD Test Guideline 109 (2012), Regulation (EC) No 440/2008 Method A.3. and EPA OCSPP Test Guideline OPPTS 830.7300 (2002), the Relative Density of the test item Boc-L-hydroxyproline at 20 °C ± 0.01 °C (compared to water at 4 °C) is determined to be: 1.222