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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Endpoint:
thermal stability
Type of information:
experimental study
Adequacy of study:
key study
Study period:
09.01. - 19.02.2015
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
comparable to guideline study

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2015
Report date:
2015

Materials and methods

Test guideline
Qualifier:
according to guideline
Guideline:
other: Differentialthermoanalysis (DSC), Lab method SOP SPZ-420
Version / remarks:
Screening test
Deviations:
no
Principles of method if other than guideline:
Determination of thermal stability with Differential Scanning Calorimetry (DSC) method
GLP compliance:
no
Other quality assurance:
ISO/IEC 17025 (General requirements for the competence of testing and calibration laboratories)

Test material

Constituent 1
Chemical structure
Reference substance name:
(2S,4R)-1-[(tert-butoxy)carbonyl]-4-hydroxypyrrolidine-2-carboxylic acid
EC Number:
604-011-7
Cas Number:
13726-69-7
Molecular formula:
C10H17NO5
IUPAC Name:
(2S,4R)-1-[(tert-butoxy)carbonyl]-4-hydroxypyrrolidine-2-carboxylic acid
Test material form:
solid
Details on test material:
- State of aggregation: solid

Results and discussion

For thermal stability study

Sublimation:
no
Transformation products:
no

For study on stability to sunlight

Test substance stable to sunlight:
not determined

For study on stability to metals

Test substance stable to metals / metal ions:
not determined

Any other information on results incl. tables

No exothermic reaction observed.


In the measuring range 30 - 400 °C, the sample shows endothermic effects in temperature ranges of approx. 115 - 155 °C (without loss in mass), 195 - 215 °C and 255 - 280 °C.


Loss in mass at the end of study is 53%.

Applicant's summary and conclusion

Conclusions:
No exothermic reaction observed.