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Physical & Chemical properties

Water solubility

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Reference
Endpoint:
water solubility
Type of information:
experimental study
Adequacy of study:
key study
Study period:
1996
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
guideline study with acceptable restrictions
Qualifier:
according to guideline
Guideline:
EU Method A.6 (Water Solubility)
Version / remarks:
(1992)
Deviations:
not specified
GLP compliance:
yes
Type of method:
flask method
Water solubility:
< 0.27 mg/L
Temp.:
20 °C
pH:
6.4
Details on results:
According to X-ray powder diffraction the starting material batch and the insoluble residues from water consist of the same solid state form.
Conclusions:
Interpretation of results (migrated information): insoluble (< 0.1 mg/L)
The solubility of the substance in aqueous buffer solution (pH = 6.4) determined with the flask method at 20 °C was measured to be < 0.27 mg/L.
Executive summary:

The water solubility of the substance was determined according to EC guidance A.6 using the flaks method. The test item showed a solubility value of < 0.27 mg/L at 20 °C. The pH value was 6.4.

Description of key information

The solubility of the substance in aqueous buffer solution (pH = 6.4) determined with the flask method at 20 °C was measured to be < 0.27 mg/L . 

Key value for chemical safety assessment

Water solubility:
0.27 mg/L
at the temperature of:
20 °C

Additional information

'Should be read as < 0.27 mg/L'