Registration Dossier

Data platform availability banner - registered substances factsheets

Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Ecotoxicological information

Short-term toxicity to aquatic invertebrates

Currently viewing:

Administrative data

Link to relevant study record(s)

Description of key information

No toxic effects against Daphnia were observed at a limit effective loading of 100 mg/L.

The results are expressed in terms of Effective Loadings (EL) (Neuhahn, 2015).

Key value for chemical safety assessment

Fresh water invertebrates

Fresh water invertebrates
Effect concentration:
100 mg/L

Additional information

"Should read: >100 mg/L"

A study was performed to assess the acute toxicity of 1,3-bis(3-isocyanato-4-methylphenyl)-1,3-diazetidine-2,4-dione toDaphnia magnaSTRAUS under static conditions. The study was conducted in accordance with the Council Regulation (EC) No 440/2008, Method C.2 ‘Acute toxicity forDaphnia’ (2008) which is equivalent to OECD Guideline for Testing of Chemicals No. 202 'Daphniasp., Acute Immobilisation Test' (adopted April 13, 2004). TheDaphniawere exposed to a limit test concentration of nominally 100 mg/L dissolved in dilution water. Auxiliaries used to prepare the test media were an ultrasonic bath, a magnetic stirrer and a folded filter and an aseptic filter. Observations were made on the swimming ability and the immobilisation rate, respectively, after 24 and 48 hours of exposure. No toxic effects againstDaphniawere observed at a limit of water solubility under exposure conditions. The results are expressed in terms of Effective Loadings (EL). Water Accommodated Fractions (WAF) were used to test effects at limit effective loadings, no specific analysis was performed and the content of the test item during the exposure period was verified by DOC determination. This toxicity study is classified as acceptable and satisfies the guideline requirements for the acuteDaphniastudy.