Registration Dossier
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EC number: 261-693-5 | CAS number: 59312-61-7
Water solubility
Administrative data
Link to relevant study record(s)
- Endpoint:
- water solubility
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 08 September 2015 to 20 September 2015
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 105 (Water Solubility)
- Deviations:
- no
- Qualifier:
- according to guideline
- Guideline:
- EU Method A.6 (Water Solubility)
- Deviations:
- no
- GLP compliance:
- no
- Type of method:
- flask method
- Specific details on test material used for the study:
- SOURCE OF TEST MATERIAL
- Code number of the test material as used in the study report: FAT 93460/D
- Source and lot/batch No. of test material: Lot. 20140721 - Key result
- Water solubility:
- < 0.7 µg/L
- Conc. based on:
- test mat.
- Temp.:
- 20 °C
- Remarks on result:
- other: pH details are not available
- Details on results:
- - The preliminary visual experiments showed that the water solubility of the test item is below 10 mg/L.
- Flask-Method: Average 3 experiments: <0.7 μg/L. The recovery of 107 % indicates a sufficient accuracy of the analytical method. - Conclusions:
- The water solubility of the test item at a temperature of 20 °C was determined to be <0.7 μg/L (without correction for the purity).
- Executive summary:
The water solubility of the test substance was evaluated in a study conducted according to OECD Guideline 105 and EU Method A.6. Flask method was used for this purpose. Based on the findings of the study, the water solubility of the test substance at a temperature of 20 °C was determined to be <0.7 μg/L (without correction for the purity).
Reference
Preliminary Visual Estimation of the Water Solubility
Amount of the test item in mg | Total volume in ml | Appearance of mixture |
10 | 10 | undissolved |
50 | undissolved | |
100 | undissolved | |
1000 | undissolved |
Flask Method
Experiment | A | B | C | D (blank) |
Amount of test item [mg] | 3000 | 3000 | 3000 | - |
Stirring time at 30 °C [h] | 24 | 48 | 72 | 72 |
Measured concentration [µg/l] |
n.d. (<0.7) |
n.d. (<0.7) |
n.d. (<0.7) |
- |
Dilution | undiluted | undiluted | undiluted | - |
Water solubility [µg/l] | <0.7 | <0.7 | <0.7 | - |
Description of key information
The water solubility of the test substance was evaluated in a study conducted according to OECD Guideline 105 and EU Method A.6. Flask method was used for this purpose. Based on the findings of the study, the water solubility of the test substance at a temperature of 20 °C was determined to be <0.7 μg/L (without correction for the purity).
Key value for chemical safety assessment
- Water solubility:
- 0.7 µg/L
- at the temperature of:
- 20 °C
Additional information
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
