Registration Dossier
Registration Dossier
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EC number: 203-540-7 | CAS number: 107-99-3
Short-term toxicity to aquatic invertebrates
Administrative data
Link to relevant study record(s)
Description of key information
Acute aquatic toxicity on Daphnia of the target chemical was estimated by using the following predictors: VEGA EPA and DEMETRIA models and ECOSAR. The predictors were employed in order to apply a weight of evidence approach to enhance the reliability of the predictions. In the weight of evidence assessment only reliable predictions are to be taken into account. 48-h LC50 predictions are the following: 25.16 mg/L (VEGA/EPA – moderate reliable), 4.48 mg/L (VEGA/DEMETRIA – low reliable) and 13.466 mg/L (ECOSAR).
The weight of evidence assessment led to a 48-h LC50 prediction for acute aquatic toxicity in Daphnia equal to 13.466 mg/L. The weight of evidence prediction was assessed as moderate reliable.
Key value for chemical safety assessment
Fresh water invertebrates
Fresh water invertebrates
- Effect concentration:
- 13.466 mg/L
Additional information
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