(1R)-1-[(4R,4aR,8aS)-2,6-bis(3,4-dimethylphenyl)tetrahydro[1,3]dioxino[5,4-d][1,3]dioxin-4-yl]ethane-1,2-diol

Biodegradation in water: screening tests

Administrative data

Endpoint:

biodegradation in water: ready biodegradability

Type of information:

experimental study

Adequacy of study:

key study

Reliability:

other: All information in this endpoint has been provided by the ECHA using the 12 year rule, this is data is not owned by the registrant. The reliability is estimated to be at level 2 at a minimum.

Rationale for reliability incl. deficiencies:

other: see 'Remark'

Remarks:

All information in this endpoint has been provided by the ECHA using the 12 year rule, this is data is not owned by the registrant. The reliability is estimated to be at level 2 at a minimum. Therefore the reliability statement below can be used: Study conducted in accordance with generally accepted scientific principles, possibly with incomplete reporting or methodological deficiencies, which do not affect the quality of relevant results.

Data source

Reference

Reference Type:

other: Body responsible for the test

Title:

Unnamed

Materials and methods

Test guideline

Qualifier:

according to guideline

Guideline:

OECD Guideline 301 B (Ready Biodegradability: CO2 Evolution Test)

Deviations:

not specified

GLP compliance:

yes

Test material

Test material information

Constituent 1

Reference substance name:

-

EC Number:

413-110-2

EC Name:

-

Cas Number:

135861-56-2

Molecular formula:

C24H30O6

IUPAC Name:

(1R)-1-[(4R,4aR,8aS)-2,6-bis(3,4-dimethylphenyl)tetrahydro[1,3]dioxino[5,4-d][1,3]dioxin-4-yl]ethane-1,2-diol

Details on test material:

This information not provided in the migrated SNIF dossier (SNIF # 001-3.0.10-01) provided by ECHA

Study design

Oxygen conditions:

aerobic

Inoculum or test system:

other: This information not provided in the migrated SNIF dossier (SNIF # 001-3.0.10-01) provided by ECHA

Details on inoculum:

This information not provided in the migrated SNIF dossier (SNIF # 001-3.0.10-01) provided by ECHA

Duration of test (contact time):

28 d

Initial test substance concentration

Based on:

other: This information not provided in the migrated SNIF dossier (SNIF # 001-3.0.10-01) provided by ECHA

Parameter followed for biodegradation estimation

Parameter followed for biodegradation estimation:

other: This information not provided in the migrated SNIF dossier (SNIF # 001-3.0.10-01) provided by ECHA

Details on study design:

This information not provided in the migrated SNIF dossier (SNIF # 001-3.0.10-01) provided by ECHA

Reference substance

Reference substance:

other: Sodium acetate

Results and discussion

Preliminary study:

This information not provided in the migrated SNIF dossier (SNIF # 001-3.0.10-01) provided by ECHA

Test performance:

This information not provided in the migrated SNIF dossier (SNIF # 001-3.0.10-01) provided by ECHA

% Degradation

Parameter:

% degradation (CO2 evolution)

Value:

28

Sampling time:

28 d

Details on results:

Points of degradation plot (test substance):
4% degradation after 2 days
11% degradation after 6 days
18% degradation after 10 days
23% degradation after 14 days
28% degradation after 28 days

BOD5 / COD results

Results with reference substance:

Points of degradation plot (reference substance):
24% degradation after 2 days
69% degradation after 6 days
88% degradation after 10 days
100% degradation after 14 days

Applicant's summary and conclusion

Validity criteria fulfilled:

yes

Interpretation of results:

other: not readily biodegradable

Conclusions:

The test substance was shown not to be readily biodegradable under the conditions of the test.

Executive summary:

All information in this endpoint has been provided by the ECHA using the 12 year rule, this is data is not owned by the registrant.

Rate of ready biodegradation was determined by using OECD Guideline 301B Annex V - Method C4

T-1540N was demonstrated not to be readily biodegradable under the conditions of the test.