Registration Dossier

Diss Factsheets

Administrative data

Endpoint:
carcinogenicity
Type of information:
(Q)SAR
Adequacy of study:
key study
Study period:
June, 2010
Reliability:
2 (reliable with restrictions)
Justification for type of information:
QSAR prediction: migrated from IUCLID 5.6

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2010
Report date:
2010

Materials and methods

Test guideline
Qualifier:
no guideline followed
Principles of method if other than guideline:
In silico prediction using DEREK.
GLP compliance:
not specified

Test material

Constituent 1
Chemical structure
Reference substance name:
1-(3-chlorophenyl)-4-(3-chloropropyl)piperazinium chloride
EC Number:
258-038-0
EC Name:
1-(3-chlorophenyl)-4-(3-chloropropyl)piperazinium chloride
Cas Number:
52605-52-4
Molecular formula:
C13H18Cl2N2.ClH
IUPAC Name:
1-(3-chlorophenyl)-4-(3-chloropropyl)piperazin-1-ium chloride

Results and discussion

Effect levels

Basis for effect level:
other: DEREK evaluation showed alert for carcinogenicity.

Applicant's summary and conclusion

Conclusions:
Derek evaluation for the test item showed an alerts. Carcinogenicity in mammals (including humans) is plausible.