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Physical & Chemical properties

Partition coefficient

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Description of key information

Based on the determination of the water solubility (0.23 mg/L)  and the octanol solubility  (>1- >100 kg/L) of the analogues, the logPow of the analogues was calculated to be >6.6 and >8.63 (Laus, 2015a and b).

Key value for chemical safety assessment

Log Kow (Log Pow):
6.6

Additional information

The calculation of the logPow of DDNSA based on the water solubility and octanol solubility is two orders of magnitude above that of the structural analogue DNNSA. This is solely caused by the determination of the solubility in octanol, where for DDNSA higher loading rates were included in the test design. A high logPow is confirmed by the outcome of a QSAR on a representative structure for CaDDNSA. In view of the structural similarities with both acids, the logPow for CaDDNSA is set at > 6.6 in a worst case approach because this value is most close to the EUSES cut-off value (logPow 6).