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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Link to relevant study record(s)

Description of key information

EC50 Daphnia magna 48h for Sulfadimidine = 31.4 mg/l

Key value for chemical safety assessment

Fresh water invertebrates

Fresh water invertebrates
Effect concentration:
31.4 mg/L

Additional information

Some data regarding short-term toxicity to aquatic invertebrates are reported in database ECOTOX, EPA for Sulfadimidine CAS 57-68-1:

- EC50 Daphnia magna 48h = values 31.4, 39, 109.5 and 185.3 base on different light source used (ref. Jung et all, Ecotoxicology 17(1): 37-45, 2008. Specific experimental condition are explained in the abstract free available on website : The lighting conditions were as follows: (1) fluorescent light only, (2) continuous irradiation with 15 microW/cm(2) UVB, (3) pulsed irradiation with 90 microW/cm(2) UVB for 4 h/d, and (4) natural sunlight (outdoors). Laboratory tests showed that phototoxicity resulting from exposure to continuous UVB light generally increased the acute toxicity of the sulfonamides in Daphnia magna.)

- EC50 Daphnia magna 48h = 174.4 mg/l (ref. Kim et all, Environ. Int.33(3): 370-375, 2007)

- EC50 Daphnia magna 48h = 202 mg/l (ref. De Liguoro, Chemosphere75(11): 1519-1524, 2009)

- EC50 Daphnia magna 48h = 215.9 mg/l (ref. Park et all, Ecotoxicology17(6): 526-538, 2008)


According to the CLP Regulation (EC n.1272/2008) the data of short-term toxicity to aquatic invertebrates for Sulfadimidine are of no concern for acute aquatic toxicity.