Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Environmental fate & pathways

Endpoint summary

Administrative data

Description of key information

Additional information


As reported in the summary of environmental fate and exposure in HSDB Report of Sulfamethazine (synonym of Sulfadimidine) by Scientific Review Committee, Koc values ranging from 49 to 208 (many references: Thiele-Bruhn S et all, Arch Environ Contam Toxicol 47: 31-39, 2004; Boxall et all, Rev Environ Contam Toxicol 180: 1-91, 2004; Tolls, Environ Sci Technol 35: 3397-406, 2001; Thiele-Bruhn, J Plant Nutr Soil Sci. 166: 145-167, 2003 )indicate that Sulfadimidine is not expected to adsorb to suspended solids and sediment. A low Koc for Sulfadimidine is predicted also by KOCWIN v.2.00 (Koc = 191.3 MCI Method equivalent to log Koc = 2.282).

Column 2 of REACH Annexes VIII and IX provides the following exemptions: "The study does not need to be conducted if based on the physicochemical properties the substance can be expected to have a low potential for adsorption (e.g. the substance has a low octanol water partition coefficient)"

The Sulfadimidine has got log Kow = 0.19 which can be considered of no concern.