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Physical & Chemical properties

Water solubility

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Reference
Endpoint:
water solubility
Type of information:
other: Expert Statement
Adequacy of study:
key study
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: An expert statement based on all available literature data
Qualifier:
no guideline required
Principles of method if other than guideline:
expert statement
GLP compliance:
no
Type of method:
other: An expert statement based on all available literature data
Water solubility:
ca. 1.2 g/L
Temp.:
25 °C
Remarks on result:
other: The average (n = 2) reported water solubility

Reference

Klimisch

Code

Temp.

(°C)

Water

Solubility

(g/L)

Method

Varhanickova, Dana; Shiu, Wan-Ying; Mackay, Donald, Aqueous Solubilities of Alkylphenols and Methoxyphenols at 25 °C. J. Chem. Eng. Data (1995), 40(2), 448-51.

2*

25

1.42

HPLC

Blackman, G.E.; Parke, M.H.; Garton, G.; The physiological activity of substituted phenols. II. Relations between physical properties and physiological activity.

Arch. Biochem. and Biophys. (1955), 54, 55-71.

2

25

1.01

Colorimetric

Average

 

 

 

1.21

Deviation

 

 

 

0.21

Rel. Dev.

 

 

 

17%

* Reliable with restrictions (Klimisch et al., 1987)

The average (n = 2) reported water solubility of TMP is 1.2±0.2 g/L at 25°C. The reported water solubility data were considered to have a Klimisch code of 2, indicating that they were “well documented and scientifically acceptable”(Klimisch et al., 1987).

REFERENCES

Klimisch H.J.; Andreae M.; Tillmann U.; A systematic approach for evaluating the quality of experimental toxicological and ecotoxicological data. Reg. Toxicol. Pharmacol.(1987), 28, 1-5.

Conclusions:
Interpretation of results (migrated information): soluble (1000-10000 mg/L)
The average (n = 2) reported water solubility of the test substance is 1.2 ± 0.2 g/L at 25 °C.

Description of key information

Key value for chemical safety assessment

Water solubility:
1.2 g/L
at the temperature of:
25 °C

Additional information