Registration Dossier
Registration Dossier
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EC number: 259-105-7 | CAS number: 54326-11-3
Toxicity to microorganisms
Administrative data
Link to relevant study record(s)
Description of key information
Based on read across the No Observed Effect Concentration (NOEC) of (benzoato-O,O')hydroxy(octadecanoato-O,O')aluminium to aquatic micro-organisms is predicted to be 15.4 mg/L.
Key value for chemical safety assessment
- EC10 or NOEC for microorganisms:
- 15.4 mg/L
Additional information
As no data was available for the toxicity to microorganisms of (benzoato-O,O')hydroxy(octadecanoato-O,O')aluminium, the endpoint was read across from aluminum, benzoate C16-18-fatty acids complexes.The toxicity of the read-across substance to activated sewage sludge was taken from the toxicity control of a proprietary, GLP-compliant ready biodegradability CO2 evolution test following OECD guideline 301B (Harlan 2013). In the toxicity control, the biodegradation rate of a reference substance known to be readily biodegradable is followed in the presence of the test item. The test item did not exhibit any inhibitory effects on the biodegradation rate of the reference substance, indicating that it was not toxic to the microorganisms at the concentration tested.
Aluminum, benzoate C16-18-fatty acids complexes (CAS No. 94166-87-7, EC No. 303-385-6) is considered suitable for read across to (benzoato-O,O')hydroxy(octadecanoato-O,O')aluminium as it is structurally similar being an approximate 2:1 mixture of (benzoato-O,O')hydroxy(octadecanoato-O,O')aluminium and (benzoato-O,O')hydroxy(hexadecanoato-O,O')aluminium. The only significant difference is the presence of about 30% of the aluminium complex containing the saturated C16-fatty acid, hexadecanoate, in place of the saturated C18-fatty acid, octadecanoate. This small difference in composition is expected to have no adverse influence on the toxicity to microorganisms.
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