Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 245-821-7 | CAS number: 23680-84-4
Endpoint summary
Administrative data
Description of key information
Appearance:
On the basis of physical observation and using the sense of smell, 2-chloro-6,7-dimethoxyquinazolin-4-amine was determine to be a solid white powder.
Melting point:
Melting point 2-chloro-6,7-dimethoxyquinazolin-4-amine of is determine to be 275.5 Deg C.
Boiling Point:
Based on prediction done using MPBPVP v1.43, the Boiling point of 2-chloro-6,7-dimethoxyquinazolin-4-amine was estimated to be 376.85 ˚C.
Density:
Density of 2-chloro-6,7-dimethoxyquinazolin-4-amine determine to be 1.5062 g/cm3 at temperature 25 Deg C.
Particle size distribution:
The particle size distribution of test item 2-chloro-6,7-dimethoxyquinazolin-4-amine was determined by granulometric analysis. The particle size distribution was determined to be in the range of 150 micron to 53 micron.
Vapour pressure:
The estimated vapour pressure of 2-chloro-6,7-dimethoxyquinazolin-4-amine at 25 deg C was 0.000199 Pa.
Partition coefficient:
Based on the available data from modeling databases using the KOWWIN V1.68 program, the partition coefficient (log Pow) value of the substance 2 -Chloro-6,7 -dimethoxyquinazolin-4 -amine was estimated to be 1.5. On the basis of this value, chemical 2-Chloro-6,7-dimethoxyquinazolin-4-amine can be considered to be hydrophilic in nature.
Water solubility:
The estimated water solubility of 2-chloro-6,7-dimethoxyquinazolin-4-amine was 1418 mg/l at temperature 25 deg C.
Surface tension:
Based on the data from ACD labs, surface tension for 2-chloro-6,7-dimethoxyquinazolin-4-amine was predicted to be 0.0757 N/m.
Flash point:
Flash point of 2-chloro-6,7-dimethoxyquinazolin-4-amine is calculated at 1 atm. Pressure to be 198.40 Deg C.
Auto flammability:
2-chloro-6,7-dimethoxyquinazolin-4-amine did not catch fire on being exposed to air at room temperature of 27°C pressure of 966 hPa. This indicates that 2-chloro-6,7 -dimethoxyquinazolin-4-amine is not auto-flammable.
Flammability:
2-chloro-6,7-dimethoxyquinazolin-4-amine does not indicate any ignition when the flame of bunsen burner having temperature of approximately 950°C is brought in contact with it. Thus it can be concluded that 2-chloro-6,7-dimethoxyquinazolin-4-amine is not flammable at high temperature. However since such high temperatures are not found under normal circumstances of transportation and use, thus 2-chloro-6,7-dimethoxyquinazolin-4-amine was considered non-flammable for chemical safety assessment.
Explosiveness:
The study does not need to be conducted because there are no chemical groups present in the molecule which are associated with explosive properties.
Oxidizing properties:
The study does not need to be conducted because the organic substance contains oxygen or halogen atoms which are chemically bonded only to carbon or hydrogen and hence, the classification procedure does not need to be applied.
Additional information
Appearance:
On the basis of physical observation and using the sense of smell, 2-chloro-6,7-dimethoxyquinazolin-4-amine was determine to be a solid white powder.
Melting point:
Melting point 2-chloro-6,7-dimethoxyquinazolin-4-amine of is determine to be 275.5 Deg C.
From other reliable sources it is concluded that Melting point of 2 -chloro-6,7 -dimethoxyquinazolin-4 -amine is in the range between 276 to 278 Deg C.
Boiling Point:
Based on the prediction done using the EPI Suite MPVPBP V1.43, the Boiling point of 2-chloro-6,7-dimethoxyquinazolin-4-amine was predicted.
The boiling point of 2-chloro-6,7-dimethoxyquinazolin-4-amine was estimated to be 376.85 ˚C.
Density:
Density of 2-chloro-6,7-dimethoxyquinazolin-4-amine determine to be 1.5062 g/cm3 at temperature 25 Deg C.
From other reliable sources it is concluded that density of 2 -chloro-6,7 -dimethoxyquinazolin-4 -amine is 1.3568 g/cm3 at temperature 25 Deg C.
Particle size distribution:
The particle size distribution of test item 2-chloro-6,7-dimethoxyquinazolin-4-amine was determined by granulometric analysis. The particle size distribution was determined to be in the range of 150 micron to 53 micron.
Vapour pressure:
Modified Grain method was used to estimate the vapour pressure of 2 -chloro-6,7 -dimethoxyquinazolin-4 -amine using MPBPVP v1.43 of EPI SUITE.
The estimated vapour pressure of 2 -chloro-6,7 -dimethoxyquinazolin-4 -amine at 25deg C was 0.000199 Pa.
Partition coefficient:
Based on the available data from modeling databases using the KOWWIN V1.68 program, the partition coefficient (log Pow) value of the substance 2 -Chloro-6,7 -dimethoxyquinazolin-4 -amine was estimated to be 1.5. On the basis of this value, chemical 2-Chloro-6,7-dimethoxyquinazolin-4-amine can be considered to be hydrophilic in nature.
Water solubility:
WATERNT v1.01 was used to estimate the water solubility of 2-chloro-6,7-dimethoxyquinazolin-4-amine. The estimated water solubility of 2-chloro-6,7-dimethoxyquinazolin-4 -amine was 1418 mg/l at 25 deg C.
Based on this value, 2-chloro-6,7-dimethoxyquinazolin-4-amine was considered to be soluble in water.
Surface tension:
Based on the data from ACD labs, surface tension for 2-chloro-6,7-dimethoxyquinazolin-4-amine was predicted to be 0.0757 N/m.
Flash point:
Flash point of 2-chloro-6,7-dimethoxyquinazolin-4-amine is calculated at 1 atm. Pressure to be 198.40 Deg C.
Auto flammability:
2-chloro-6,7-dimethoxyquinazolin-4-amine did not catch fire on being exposed to air at room temperature of 27°C pressure of 966 hPa. This indicates that 2-chloro-6,7 -dimethoxyquinazolin-4-amine is not auto-flammable.
Flammability:
2-chloro-6,7-dimethoxyquinazolin-4-amine does not indicate any ignition when the flame of bunsen burner having temperature of approximately 950°C is brought in contact with it. Thus it can be concluded that 2-chloro-6,7-dimethoxyquinazolin-4-amine is not flammable at high temperature. However since such high temperatures are not found under normal circumstances of transportation and use, thus 2-chloro-6,7-dimethoxyquinazolin-4-amine was considered non-flammable for chemical safety assessment.
Explosiveness:
The study does not need to be conducted because there are no chemical groups present in the molecule which are associated with explosive properties.
Oxidizing properties:
The study does not need to be conducted because the organic substance contains oxygen or halogen atoms which are chemically bonded only to carbon or hydrogen and hence, the classification procedure does not need to be applied.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
