3-methylpyrazole

Water solubility

Link to relevant study record(s)

Reference

Endpoint:

water solubility

Type of information:

experimental study

Adequacy of study:

key study

Study period:

2011-05-17 - 2011-08-03

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

guideline study

Qualifier:

according to guideline

Guideline:

OECD Guideline 105 (Water Solubility)

Deviations:

yes

Remarks:

As the test item very well soluble in water, it was not possible to weigh the fivefold saturation concentration of the test item in water in order to perform a main study as described in the guidelines.

GLP compliance:

yes (incl. QA statement)

Type of method:

flask method

Key result

Water solubility:

> 1 000 g/L

Temp.:

20 °C

Remarks on result:

other: The solubility of 3-Methylpyrazol was considered to be "miscible with water in all proportions".

Conclusions:

Interpretation of results: very soluble (> 10000 mg/L)
The results of the main study indicate that 3-Methylpyrazol is miscible with water in all proportions at two different temperatures (room temperature and 5 °C).

Executive summary:

The results of the main study indicate that 3-Methylpyrazol is miscible with water in all proportions at two different temperatures (room temperature and 5 °C). Therefore, it was not possible to weigh the fivefold saturation concentration of the test item in water in order to perform a main study as described in the guidelines.

Description of key information

3-Methylpyrazol is miscible with water in all proportions at two different temperatures (room temperature and 5 °C).

Key value for chemical safety assessment

Water solubility:

100 000 mg/L

at the temperature of:

20 °C

Additional information

The reported study is GLP compliant and has Klimisch score 1.

3-Methylpyrazol is miscible with water in all proportions at two different temperatures (room temperature and 5 °C). As figure for the exposure assement the upper boundary fo EUSES 2.1 is set.