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Water solubility

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Reference
Endpoint:
water solubility
Type of information:
experimental study
Adequacy of study:
key study
Study period:
2011-05-17 - 2011-08-03
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
Qualifier:
according to guideline
Guideline:
OECD Guideline 105 (Water Solubility)
Deviations:
yes
Remarks:
As the test item very well soluble in water, it was not possible to weigh the fivefold saturation concentration of the test item in water in order to perform a main study as described in the guidelines.
GLP compliance:
yes (incl. QA statement)
Type of method:
flask method
Key result
Water solubility:
> 1 000 g/L
Temp.:
20 °C
Remarks on result:
other: The solubility of 3-Methylpyrazol was considered to be "miscible with water in all proportions".
Conclusions:
Interpretation of results: very soluble (> 10000 mg/L)
The results of the main study indicate that 3-Methylpyrazol is miscible with water in all proportions at two different temperatures (room temperature and 5 °C).


Executive summary:

The results of the main study indicate that 3-Methylpyrazol is miscible with water in all proportions at two different temperatures (room temperature and 5 °C). Therefore, it was not possible to weigh the fivefold saturation concentration of the test item in water in order to perform a main study as described in the guidelines.

Description of key information

3-Methylpyrazol is miscible with water in all proportions at two different temperatures (room temperature and 5 °C).

Key value for chemical safety assessment

Water solubility:
100 000 mg/L
at the temperature of:
20 °C

Additional information

The reported study is GLP compliant and has Klimisch score 1.

3-Methylpyrazol is miscible with water in all proportions at two different temperatures (room temperature and 5 °C). As figure for the exposure assement the upper boundary fo EUSES 2.1 is set.