Registration Dossier
Registration Dossier
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EC number: 232-318-2 | CAS number: 8003-22-3 This substance is identified in the Colour Index by Colour Index Constitution Number, C.I. 47000.
Endpoint summary
Administrative data
Description of key information
Additional information
Stability
Hydrolysis:
The Hydrolysis rate constant of D&C Yellow No. 11 is estimated to be 0.0000000000289682 cm3/molecule-sec at half-life of 4.431hrs. The estimated half-life of the substance indicates that the substance D&C Yellow No. 11 is moderately hydrolysable.
Biodegradation
Biodegradation in water:
The screening test inherent to the biodegradability of the substance was calculated using the software BIOWIN v4.10.
The results indicate that C.I. Solvent Yellow 33 is not expected to be readily biodegradable.
Biodegradation in water and sediment:
Half life period of C.I. Solvent Yellow 33 in water is observed to be 37.5 days (900 hrs.) while in sediment it is 337.5 days (8100 hrs). Based on these half life values of C.I. Solvent Yellow 33 , it is concluded that the chemical is not persistent in water and sediment.
Biodegradation in soil:
EPI Suite has estimated that C.I. Solvent Yellow 33 is expected to be found not predominantly in soil and its not persistence estimate is based on its transformation in this medium. Its half-life in soil, 75 days (1800 hrs), does exceeds the threshold of 120 days as per Annex XIII of REACH.
Therefore, C.I. Solvent Yellow 33 is estimated to be not persistent in the soil environment.
Bioaccumulation
Bioaccumulation: aquatic / sediment:
The estimated bioconcentration factor (BCF) for C.I. Solvent Yellow 33 is 61.25 L/kg, that does not exceed the bioconcentration threshold of 2000. Thus it is concluded that C.I. Solvent Yellow 33 is not expected to bioaccumulate in the food chain because it does not exceed the BCF criteria.
Transport and distribution:
Adsorption/ desorption:
The partition coefficient of test item 1,3-isobenzofurandione, reaction products with methylquinoline and quinoline (CAS No.8003-22-3)was determined as per the HPLC method (OECD Guideline-12). The Log Koc value was found to be 3.529± 0.0007 at 25°C., indicating that it is has a high sorption to soil and sediment and therefore have slight migration potential to groundwater.
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