Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 204-133-7 | CAS number: 116-26-7
Water solubility
Administrative data
Link to relevant study record(s)
- Endpoint:
- water solubility
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- From May 22, 2015 to August 12, 2015
- Reliability:
- 1 (reliable without restriction)
- Qualifier:
- according to guideline
- Guideline:
- EU Method A.6 (Water Solubility)
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 105 (Water Solubility)
- GLP compliance:
- yes (incl. QA statement)
- Type of method:
- flask method
- Key result
- Water solubility:
- 514.9 mg/L
- Temp.:
- 20 °C
- pH:
- > 3.88 - < 4
- Conclusions:
- The water solubility of SAFRANAL is 514.9 mg/L at 20 ± 1°C.
- Executive summary:
The purpose of this study was to determine the water solubility of SAFRANAL, which is specified by the saturation mass concentration of the Test Item in water at 20 ± 1°C.
During the study, the flask method (OECD 105) was applied.
The water solubility of the Test Item is given as the mean of the measured saturation concentration of SAFRANAL dissolved in water following 2 days and 3 days of equilibration, if these concentration values do not differ by more than 15%.
The results in Table 1 show that the measured concentrations after 1, 2 and 3 days do not differ by more than 15%. Thus it can be concluded that equilibrium has been reached and that the test is satisfactory.
The mean of the Test Item concentrations in the water samples obtained after 1, 2 and 3 days equilibration was 514.9 μg/mL with relative standard deviation 7 %. (Table 1.); therefore, the results meet with the accuracy criteria of the OECD 105 guide.
Table 1. The Test Item concentration of the water samples after 1 day, 2 days and 3 days equilibration
Equilibration time Test item (µg/mL) Mean (µg/mL) RSD % 1 day 532.0 532.5 0.6 529.7 536.0 2 days 514.5 522.2 1.3 527.2 524.8 3 days 487.7 498.9 0.4 491.0 491.2 MEAN: (WATER SOLUBILITY) 514.9 - RSD %: 7 - Conclusion: The water solubility of SAFRANAL is 514.9 mg/L at 20 ± 1°C.
Reference
Description of key information
The water solubility of SAFRANAL is 514.9 mg/L at 20 ± 1°C.
Key value for chemical safety assessment
- Water solubility:
- 514.9 mg/L
- at the temperature of:
- 20 °C
Additional information
Key study : OECD TG 105 , 2015 : The purpose of this study was to determine the water solubility of SAFRANAL, which is specified by the saturation mass concentration of the Test Item in water at 20 ± 1°C.
During the study, the flask method (OECD 105) was applied.
The water solubility of SAFRANAL is 514.9 mg/L at 20 ± 1°C.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
