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Physical & Chemical properties

Particle size distribution (Granulometry)

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Reference
Endpoint:
particle size distribution (granulometry)
Type of information:
experimental study
Adequacy of study:
key study
Study period:
15/06/2016 - 16/06/2016
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
Justification for type of information:
Experimental test result performed using standard test guidelines
Qualifier:
according to guideline
Guideline:
other: granulometric analysis with rotap sieve shaker.
Principles of method if other than guideline:
The particle size distribution of test substance 3-nitrobenzoic acid was determined by Granulometric analysis with Rotap sieve shaker
GLP compliance:
no
Type of method:
sieving
Type of particle tested:
primary particle
Type of distribution:
counted distribution
Percentile:
D50
Remarks on result:
other: Mass median diameter
No.:
#1
Size:
150 µm
Distribution:
47.97 %
No.:
#2
Size:
106 µm
Distribution:
21.92 %
No.:
#3
Size:
75 µm
Distribution:
12.23 %
No.:
#4
Size:
53 µm
Distribution:
10.14 %
No.:
#5
Size:
25 µm
Distribution:
2.38 %
No.:
#6
Size:
10 µm
Distribution:
0.05 %

OBSERVATION TABLE:

Amount ofTest Item weighed (g) =10.0 g            

Method run time (minutes) = 7 minutes

Sieve sizes(in microns)

Weight of petridishes (g)

Weight of petridishes +

test item (g)

Test item quantity retained after sieving (g)

Percentage (%) of test item*

150 microns

46.599

51.396

4.797

47.97 %

106 microns

44.481

46.673

2.192

21.92 %

75 microns

44.079

45.302

1.223

12.23 %

53 microns

46.890

47.904

1.014

10.14 %

25 microns

37.346

37.584

0.238

2.38 %

10 microns

44.363

44.368

0.005

0.05 %

Conclusions:
The particle size distribution of test item 2-(3,6-dihydroxy-2,4,5,7-tetraiodoxanthen-9-yl)benzoic acid, aluminium salt (CAS No. 12227-78-0) was determined by granulometric analysis with rotap sieve shaker. The particle size distribution was determined to be in the range of 150 microns to 10 microns.

Executive summary:

The particle size distribution of test item 2-(3,6-dihydroxy-2,4,5,7-tetraiodoxanthen-9-yl)benzoic acid, aluminium salt (CAS No. 12227-78-0) was determined by granulometric analysis with rotap sieve shaker. The particle size distribution was determined to be in the range of 150 microns to 10 microns.

Description of key information

The particle size distribution of test item 2-(3,6-dihydroxy-2,4,5,7-tetraiodoxanthen-9-yl)benzoic acid, aluminium salt (CAS No. 12227-78-0) was determined by granulometric analysis with rotap sieve shaker. The particle size distribution was determined to be in the range of 150 microns to 10 microns.

Additional information

The particle size distribution of test item 2-(3,6-dihydroxy-2,4,5,7-tetraiodoxanthen-9-yl)benzoic acid, aluminium salt (CAS No. 12227-78-0) was determined by granulometric analysis with rotap sieve shaker. The particle size distribution was determined to be in the range of 150 microns to 10 microns.