Registration Dossier

Diss Factsheets

Administrative data

Endpoint:
neurotoxicity
Type of information:
other: Specific neurotoxicity studies were not conducted but neurotoxicity data was evaluated from other study types and human experience.
Adequacy of study:
supporting study

Data source

Reference
Reference Type:
review article or handbook
Title:
Unnamed
Year:
2005

Materials and methods

Principles of method if other than guideline:
Method data are not available as the report details are unpublished.

GLP compliance:
not specified

Test material

Constituent 1
Chemical structure
Reference substance name:
Warfarin
EC Number:
201-377-6
EC Name:
Warfarin
Cas Number:
81-81-2
Molecular formula:
C19H16O4
IUPAC Name:
4-hydroxy-3-(3-oxo-1-phenylbutyl)-2H-chromen-2-one

Test animals

Species:
other: human

Results and discussion

Effect levels

Basis for effect level:
other: Not an organophosphorus compound, therefore acute delayed neurotoxicity studies were not conducted. No evidence of neurotoxicity from other studies and human experience
Remarks on result:
not measured/tested
Remarks:
Effect level not specified

Applicant's summary and conclusion

Conclusions:
Not an organophosphorus compound, therefore acute delayed neurotoxicity studies were not conducted. No evidence of neurotoxicity from other studies and human experience