Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Link to relevant study record(s)

Description of key information

A QSAR-derived permeability coefficient (Kp) for TAME was available. Furthermore, an experimentally derived Kp for MTBE, a highly similar substance, was available. The QSAR-derived Kp was 0.0071 cm/hour and the experimentally derived Kp of MTBE was 0.0035 cm/hour after correction for the higher temperature. For the calculation of the percentage absorption, the aqueous Kp of 0.0071 cm/hour was used.

Key value for chemical safety assessment

Absorption rate - dermal (%):
0.4

Additional information