Registration Dossier

Diss Factsheets

Administrative data

Endpoint:
partition coefficient
Type of information:
experimental study
Adequacy of study:
key study
Study period:
2010
Reliability:
1 (reliable without restriction)

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2010
Report date:
2010

Materials and methods

Test guideline
Qualifier:
according to guideline
Guideline:
OECD Guideline 117 (Partition Coefficient (n-octanol / water), HPLC Method)
GLP compliance:
yes (incl. QA statement)
Type of method:
HPLC method
Partition coefficient type:
octanol-water

Test material

Constituent 1
Chemical structure
Reference substance name:
(4Z)-hept-4-en-2-yl salicylate
EC Number:
700-488-1
Cas Number:
873888-84-7
Molecular formula:
C14H18O3
IUPAC Name:
(4Z)-hept-4-en-2-yl salicylate

Results and discussion

Partition coefficient
Type:
log Pow
Partition coefficient:
5
Temp.:
35 °C
pH:
7

Applicant's summary and conclusion

Conclusions:
The chromatograms of the test item show one peak at an average retention time of 13.07min corresponding to a partition coefficient (log value) of
5.0.
Therefore, the partition coefficient n-octanol/water of GR-86-3792: log Pow = 5.0