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Physical & Chemical properties

Water solubility

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Reference
Endpoint:
water solubility
Type of information:
experimental study
Adequacy of study:
key study
Study period:
08/10/2015
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
test procedure in accordance with generally accepted scientific standards and described in sufficient detail
Justification for type of information:
Experimental test result performed using standard test guidelines
Qualifier:
according to guideline
Guideline:
other: as mentioned below
Principles of method if other than guideline:
The water solubility determination of test item 2,4,6-trichloroaniline (CAS No; 634-93-5) was done as per the HPLC method.
GLP compliance:
not specified
Type of method:
other: HPLC method
Specific details on test material used for the study:
- Name of test material: 2,4,6-trichloroaniline
- IUPAC name: 2,4,6-Trichloroaniline
- Molecular formula : C6H4Cl3N
- Molecular weight : 196.464 g/mol
- Smiles: c1(c(cc(Cl)cc1Cl)Cl)N
- InChI: 1S/C6H4Cl3N/c7-3-1-4(8)6(10)5(9)2-3/h1-2H,10H2
- Substance type: Organic
- Physical state: Solid crystalline (Pale White to Reddish)
- Purity: >99.9%
Key result
Water solubility:
67.425 mg/L
Conc. based on:
test mat.
Temp.:
25 °C
Remarks on result:
other: no other details mentioned

TEST DESCRIPTION AND RESULT:

 

Sr. no

Sample Concentration

By % Area (mg/l)

Temperature

Dilution Factor

1

7.001

250C

10

2

6.484

250C

10

Mean

6.7425

250C

10

 

CALCULATIONS:             

 Water solubility was calculated using the formula:   

Water Solubility(mg/l)=            MeanSample concentration (mg/l)×  Dilution factor

Conclusions:
The water solubility for the test item 2,4,6-trichloroaniline (CAS No;634-93-5) was determined to be 67.425 mg/l at 25 °C.
Executive summary:

The water solubility determination of test item 2,4,6-trichloroaniline (CAS No;634-93-5) was done as per the HPLC method.

The mean water solubility was determined to be 67.425 mg/l at 25 °C.

Thus from obtained value indicate that the chemical is considered to be slightly soluble in water.

Description of key information

The water solubility for the test item 2,4,6-trichloroaniline (CAS No;634-93-5) was determined to be 67.425 mg/l at 25 °C.

Key value for chemical safety assessment

Water solubility:
67.425 mg/L
at the temperature of:
25 °C

Additional information

The water solubility determination of test item 2,4,6-trichloroaniline (CAS No;634-93-5) was done as per the HPLC method.

The mean water solubility was determined to be 67.425 mg/l at 25 °C.

Other supporting data from authoritative databases, also supported the selected key study and exhibited the water solubility of 2,4,6-trichloroaniline (CAS No; 634-93-5) as 40 mg/L at 25 °C and 38.8 mg/L at 20 °C.

Thus from obtained values indicate that the chemical is considered to be slightly soluble in water.