Registration Dossier
Registration Dossier
Diss Factsheets
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EC number: 810-844-9 | CAS number: 1803573-21-8
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data

Guidance on Safe Use
Administrative data
First-aid measures
Eye Contact: Flush with water while holding eyelids open for at least 15 minutes. Seek medical attention immediately.
Skin Contact: Remove contaminated clothing. Flush area with large amounts of water. Use soap. Seek medical attention.
Ingestion: Never give anything by mouth to an unconscious person. Wash out mouth with water. Do not induce vomiting unless directed by medical personnel. Seek medical attention immediately.
Inhalation: Remove to fresh air and keep patient at rest. Seek medical attention immediately.
Fire-fighting measures
Extinguishing Media: Extinguish fires with CO2, extinguishing powder, foam, or water.
Special Hazards Arising from the Substance or Mixture
Hazardous Combustion Products: Formation of toxic gases is possible during heating or fire. May include oxides of carbon and nitrogen and products of sulfur and bromine.
Fire / Explosion Hazards: Fine particles (such as dust and mists) may fuel fires/explosions.
Advice for Fire-Fighters
During all fire fighting activities, wear appropriate protective equipment, including self-contained breathing apparatus.
Accidental release measures
Personal Precautions, Protective Equipment and Emergency Procedures
Personnel involved in clean-up should wear appropriate personal protective equipment. Minimize exposure.
Environmental Precautions
Place waste in an appropriately labeled, sealed container for disposal. Care should be taken to avoid environmental release.
Methods and Material for Containment and Cleaning Up
Measures for Cleaning / Collecting: Contain the source of the spill if it is safe to do so. Collect spilled material by a method that controls dust generation. Avoid use of a filtered vacuum to clean spills of dry solids. Clean spill area thoroughly.
Additional Consideration for Large Spills: Non-essential personnel should be evacuated from affected area. Report emergency situations immediately. Clean up operations should only be undertaken by trained personnel.
Handling and storage
Precautions for Safe Handling
Restrict access to work area. Avoid open handling. Ground and bond all bulk transfer equipment. Minimize dust generation. Use process containment, local exhaust ventilation or perform work under fume hood/fume cupboard. Avoid inhalation and contact with skin, eyes, and clothing. When handling, use appropriate personal protective equipment. Wash hands and any exposed skin after removal of PPE. Releases to the environment should be avoided. Review and implement appropriate technical and procedural waste water and waste disposal measures to prevent occupational exposure or environmental releases. Potential points of process emissions of this material to the atmosphere should be controlled with dust collectors, HEPA filtration systems or other equivalent controls.
Conditions for Safe Storage, Including any Incompatibilities
Storage Conditions: Protect from moisture. Store at room temperature in properly labeled containers. Keep away from heat, sparks and flames.
Specific end use(s): Pharmaceutical process intermediate
Transport information
Land transport (UN RTDG/ADR/RID)
- UN number:
- UN 2811
Shipping information
- Proper shipping name and description:
- Toxic solid, organic, n.o.s. (Pyridine Compounds)
SpecialProvisionsopen allclose all
Inland waterway transport (UN RTDG/ADN(R))
- UN number:
- UN 2811
Shipping information
- Proper shipping name and description:
- Toxic solid, organic, n.o.s. (Pyridine Compounds)
Remarksopen allclose all
Marine transport (UN RTDG/IMDG)
- UN number:
- UN 2811
Shipping information
- Proper shipping name and description:
- Toxic solid, organic, n.o.s. (Pyridine Compounds)
Remarksopen allclose all
Air transport (UN RTDG/ICAO/IATA)
- UN number:
- UN 2811
Shipping information
- Proper shipping name and description:
- Toxic solid, organic, n.o.s. (Pyridine Compounds)
Remarksopen allclose all
Additional transport information
Additional information
- Special provisions / remarks / other:
- The following refers to all modes of transportation unless specified below.
This material is regulated for transportation as a hazardous material/dangerous good.
UN number: UN 2811
UN proper shipping name: Toxic solid, organic, n.o.s. (Pyridine Compounds)
Transport hazard class(es): 6.1
Packing group: III
Exposure controls / personal protection
Control Parameters
No exposure limits established.
Exposure Controls
Engineering Controls: Engineering controls should be used as the primary means to control exposures.
Personal Protective Equipment: Refer to applicable national standards and regulations in the selection and use of personal protective equipment (PPE).
Hands: Wear impervious gloves if skin contact is possible.
Eyes: Wear safety glasses as minimum protection.
Skin: Use protective clothing (uniforms, lab coats, disposable coveralls, etc.) in both production and laboratory areas.
Respiratory protection: Whenever excessive air contamination (dust, mist, vapor) is generated, respiratory protection, with appropriate protection factors, should be used to minimize exposure.
Stability and reactivity
Reactivity: No data available
Chemical Stability: Stable under normal conditions of use.
Possibility of Hazardous Reactions
Oxidizing Properties: No data available
Conditions to Avoid: Fine particles (such as dust and mists) may fuel fires/explosions. As a precautionary measure, keep away from heat sources and electrostatic discharge.
Incompatible Materials: As a precautionary measure, keep away from strong oxidizers
Hazardous Decomposition Products: No data available
Disposal considerations
Waste Treatment Methods: Dispose of waste in accordance with all applicable laws and regulations. Member State specific and Community specific provisions must be considered. Considering the relevant known environmental and human health hazards of the material, review and implement appropriate technical and procedural waste water and waste disposal measures to prevent occupational exposure and environmental release. It is recommended that waste minimization be practiced. The best available technology should be utilized to prevent environmental releases. This may include destructive techniques for waste and wastewater.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
