N-(2-aminoethyl)-1,3-propanediamine

Endpoint summary

Description of key information

The substance is considered to be acutely harmful to aquatic organisms.

Additional information

The aquatic studies were performed without analytical monitoring; however, it is assumed that the test concentrations remained stable over the exposure period based on the substance's physicochemical properties and its environmental fate. The test item is completely miscible with water (measured; see IUCLID Ch. 4.8), which is a pre-requisite to the reliable preparation of the test concentrations. The Substance will be evenly distributed in the test medium. In addition, it is highly unlikely that the Substance will precipitate from the test medium. Evaporation of the test item from the test medium is not to be expected based on the low vapour pressure of 0.036 hPa (measured at 20 °C; see IUCLID Ch. 4.6) and the low Henry's Law constant (4.17E-08 Pa*m³/mol, HENRYWIN v3.20; see IUCLID Ch. 5.4.2). In addition, the Substance is ionized at the environmentally relevant pH range (pKa = 10.51; estimated; see IUCLID Ch. 4.21), which further reduces any tendency of the Substance to evaporate into the atmosphere. Finally, loss of the test item from the test medium due to adsorption to the test vessels is unlikely as the Substance has a low adsorption potential (log Kow = -1.67, measured; see IUCLID Ch. 4.7; log Koc = 0.96 at pH 5 to 8, calculated according to Franco & Trapp; see IUCLID Ch. 5.4.1).

 

Short-term toxicity to fish

BASF AG, 1991, Rep. no. 10F0228/895368, DIN 38412, part L15, non-GLP, Leuciscus idus, static, without analytical monitoring, 96h LC50 > 220 and < 460 mg/L (not pH-adjusted), 96-h LC50 > 1000 mg/L (pH-adjusted)

Based on this result, the substance is with high probability acutely not harmful to fish.

 

Short-term toxicity to aquatic invertebrates

BASF AG, 1989, Study No. 1/0502/2/89-0503/89, DIN 38412, part 11, non-GLP, Daphnia magna, without analytical monitoring, 48h EC50 = 25.9 mg/L (not pH-adjusted)

Based on this result, the substance is considered acutely harmful to aquatic invertebrates.

 

Toxicity to aquatic algae and plants

BASF AG, 1990; Rep. no. 60E0402/043218; recalculation ECT, 2010, DIN 38412, part 9 (equivalent to OECD TG 201), Desmodesmus subspicatus, without analytical monitoring, 72h ErC10 = 9.2 mg/L, 72 h ErC50 = 460.2 mg/L (nominal; not neutralized, re-calculated); 72h ErC50 > 500 mg/L, NOErC >= 500 mg/L; LOErC >500 mg/L (nominal, neutralized, recalculated).

Based on these results, the substance is with high probability acutely and chronically not harmful to aquatic algae.

 

Toxicity to microorganisms

BASF, 1991; Rep. no. 1/91/0407/08/1, OECD 209, activated sludge, 30min EC20 = 800 mg/L.

Based on this result, the inhibition of the degradation activity of activated sludge is not anticipated when introduced in appropriate low concentrations.