Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 938-575-3 | CAS number: -
Endpoint summary
Administrative data
Description of key information
Additional information
Three studies on ready biodegradation are available for the PFAE fumarates category (i. e. 2-Butenedioic acid (E)-, didodecyl ester CAS 2402-58-6, MW 453 g/mol, 2-Butenedioic acid (E)-, ditetradecyl ester CAS 10341-03-4, MW 509 g/mol and 2-Butenedioic acid (E) -, di-C18-22-alkyl esters CAS 68921-53-9, MW 621-733 g/mol). In all tests the pass level for ready biodegradation was reached in 28 days. The strict criterion of the 10 day window however was not fulfilled for 2-Butenedioic acid (E)-, didodecyl ester CAS 2402-58-6 and 2-Butenedioic acid (E)-, ditetradecyl ester CAS 10341-03-4 (both monoconstituent substances). These substances are therefore regarded as readily biodegradable, but failing 10 day window. For 2-Butenedioic acid (E) -, di-C18-22-alkyl esters CAS 68921-53-9 the 10 day window is however not applicable, since this substance is a UVCB. This substance is therefore regarded as ready biodegradable. Based on a read across approach the remaining three members of the PFAE fumarates category (namely: 2-Butenedioic acid (2E)-, di-C12-14-alkyl esters (List No. 938-575-3), 2-Butenedioic acid (2E)-, di-C14-15-alkyl esters (List No. 938-576-9), and 2-Butenedioic acid (2E)-, di-C14-16-alkyl esters (List No 695-949-6) were assessed regarding their biodegradability using the studies mentioned above. As the pass level was reached in all tests and due to the variable composition of the remaining category members, these substances were assessed as readily biodegradable.
For two substances, namely 2-Butenedioic acid (E)-, ditetradecyl ester (CAS 10341-03-4) and 2-Butenedioic acid (E) -, di-C18-22-alkyl esters (CAS 68921-53-9) OECD 301B tests were enhanced up to 60 days, resulting in high overall degradation rates for both (87- 90% after 60 d).
CAS (EC) |
Substance name |
% degradation after 28 days |
% degradation after 60 days |
Biodegradation asssessment |
2402-58-6 (219-280-2) |
2-Butenedioic acid (E)-, didodecyl ester) |
67% (BODIS test) |
-- |
readily, but failing 10 day window |
10341-03-4 (233-739-4) |
2-Butenedioic acid (E)-, ditetradecyl ester) |
71% (OECD 301B) |
90% (OECD 301B) |
readily, but failing 10 day window |
No CAS (List No. 938-575-3) |
2-Butenedioic acid (2E) -, di-C12-14-alkyl esters |
RA: CAS 2402-58-6; 67% RA: CAS 10341-03-4; 71% RA CAS 68921-53-9; 62% |
-- |
readily biodegradable |
No CAS (List No. 938-576-9) |
2-Butenedioic acid (2E) -, di-C14-15-alkyl esters |
RA: CAS 2402-58-6; 67% RA: CAS 10341-03-4; 71% RA CAS 68921-53-9; 62% |
-- |
readily biodegradable |
1187576-41-5 (List No. 695-949-6) |
2-Butenedioic acid (2E) -, di-C14-16-alkyl esters |
RA: CAS 2402-58-6; 67% RA: CAS 10341-03-4; 71% RA CAS 68921-53-9; 62% |
-- |
readily biodegradable |
68921-53-9 (272-945-9) |
2-Butenedioic acid (E) -, di-C18-22-alkyl esters |
62% (OECD 301B) |
87% (OECD 301B) |
readily biodegradable |
The available studies cover the outer borders of this category so that this endpoint is covered by interpolation (i. e. studies are available for the lower alcohol chain lengths (C12, C14) and highest alcohol chain lengths (C18/C22), respectively). 2-Butenedioic acid (E) -, di-C18-22-alkyl esters (CAS 68921-53-9) represents the higher end of the category consisting of the longest fatty alcohol chain lengths and therefore represents a worst case for biodegradation. Thus, the assumption that all members of the PFAE fumarates category are either readily biodegradable (in case of UVCBs) or readily biodegradable, but failing 10-day window (in case of monoconstituent substances) is clearly underlined by the result for this substance (readily biodegradable). The substances are thus expected to be rapidly degraded by microorganisms in both the aquatic and terrestrial environment, therefore in accordance with Regulation (EC) No. 1907/2006, 9.2.1.2 – 9.2.1.4, further simulation testing for water and sediment or soil biodegradation are not necessary.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
