Registration Dossier
Registration Dossier
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EC number: 419-710-0 | CAS number: 42774-15-2 NYLOSTAB S-EED; NYSEED
Endpoint summary
Administrative data
Description of key information
Additional information
Acute toxicity study of the test item to earthworms was carried out according to OECD Guideline 207. The test species was Eisenia felida. The tested substance in a form of water suspension was introduced into soil in concentrations of 62.5; 125, 250, 500 and 1000 mg/kg (artificial soil dry weight). The test duration was 14 days. The animals were weighed following this time and alive animals were counted. Taking into account the obtained results it was assessed that the test item did not cause mortality of earthworms, and changes in behaviour and appearance of earthworms, in relation to the control, were not observed.
It was found that:
median lethal concentration causing 50% of mortality of earthworms population (LC50) after 7 and 14 days is above 1000 mg/kg and the highest concentration, used in experiment, causing no mortality of earthworms (LCo) after 7 and 14 days is also 1000 mg/kg.
The assessment of the test item on growth and emergence of three terrestrial plant species was carried out according to OECD Guideline No 208 and Good Laboratory Practice (GLP). For testing the following species were used: wheat (Triticum aestivum L. Emend. Fiori et Pao!.), rape (Brassica rapa L. Emend. Metzg. ssp. rapa) and lettuce (Lactuca sativa L. Var. Longifolia Lam.) The following test concentrations were used:1, 10 and 100 mg/kg ( soil dry weight).
Taking into account the obtained results it was assessed that the test substance did not effect emergence and growth in relation to the control. Phytotoxic effects of the test substance on plants were not observed.
The concentration at which the change in emergence is 50% of that of the control (LC5o) is above 100 mg/kg dry soil. The concentration at which the change in growth is 50% of that of the control (EC5o) is above 100 mg/kg dry soil.
NOEC for all species and endpoints is 100 mg/kg(soil dry weight).Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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