Registration Dossier
Registration Dossier
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EC number: 215-687-4 | CAS number: 1344-09-8
Exposure related observations in humans: other data
Administrative data
- Endpoint:
- exposure-related observations in humans: other data
- Type of information:
- other: General considerations
- Adequacy of study:
- other information
- Reliability:
- 4 (not assignable)
- Rationale for reliability incl. deficiencies:
- other: Only secondary literature (review).
Data source
Referenceopen allclose all
- Title:
- No information
- Author:
- Schleyer WL and Blumberg JG (1982). Health, safety and|environmental aspects of soluble silicates. In Soluble|Silicates, Falcone JS (ed). ACS Symposium Series 194,|Chapter 4, 49-69.
- Title:
- No information
- Author:
- Select Committee on GRAS Substances, Evaluation of the Health Aspects of Certain Silicates as Food Ingredients, SCOGS-61, Federation of American Societies for Experimental Biology, NTIS Publication 301-402/AS, Springfield, Va., p.4, 1979.
Materials and methods
- Type of study / information:
- Type of experience: other
- Principles of method if other than guideline:
- General scientific considerations.
Test material
- Reference substance name:
- Silicic acid, sodium salt
- EC Number:
- 215-687-4
- EC Name:
- Silicic acid, sodium salt
- Cas Number:
- 1344-09-8
- Molecular formula:
- Na2O x (SiO2)n with Molar Ratio (MR) (SiO2/Na2O): 1.5 – 4
- IUPAC Name:
- sodium hydroxy(oxo)silanolate
- Details on test material:
- TS-Freetext:
Sodium silicate, no further information on molar ratio and
concentration given.
Constituent 1
Results and discussion
Any other information on results incl. tables
RM-Freetext:
In man, the lethal oral dose of sodium silicates has been
estimated as 0.5-5 g/kg, depending on the molar ratio.
In the USA sodium silicate is considered "generally
recognized as safe (GRAS)" for indirect food uses, and as
additive to drinking water in concentrations of up to 100
ppm.
Applicant's summary and conclusion
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