Amines, polyethylenepoly-, tetraethylenepentamine fraction

Melting point / freezing point

Link to relevant study record(s)

Reference

Reference 1

Endpoint:

melting point/freezing point

Type of information:

experimental study

Adequacy of study:

supporting study

Study period:

04 - 12 Feb 2010

Reliability:

2 (reliable with restrictions)

Rationale for reliability incl. deficiencies:

guideline study with acceptable restrictions

Qualifier:

according to guideline

Guideline:

OECD Guideline 102 (Melting point / Melting Range)

Version / remarks:

27th July 1995

Deviations:

yes

Remarks:

Only one temperature: -25 °C

Qualifier:

according to guideline

Guideline:

EU Method A.1 (Melting / Freezing Temperature)

Version / remarks:

18 march 2002

Deviations:

yes

Remarks:

Heating was omitted

Principles of method if other than guideline:

Deviations from guideline:
The sample is a fluid at +20 °C, so heating can be omitted
From literature it can be assumed, that the freezing point is under -20 °C.
For REACH the freezing point only has to be determined till a lower limit of -20 °C,so: A pour point analysis is performed at only one temperature: -25 °C
The measure to avoid super cooling was adding a few anti bumping granules.
The deviations will not lead to a different conclusion, only simplify the method.

GLP compliance:

no

Type of method:

pour point

Melting / freezing pt.:

< -20 °C

Atm. press.:

101 325 Pa

After one week at below -25 °C the surface of the substance moves, the substance is still fluid. A small rise in temperature may have occurred by removing the tubes from the freezer, but it is save to conclude the freezing point is below -20 °C for this substance.

Conclusions:

The freezing point of the substance is below -20 °C.

Reference 2

Endpoint:

melting point/freezing point

Type of information:

experimental study

Adequacy of study:

key study

Study period:

06 - 12 Apr 2010

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

guideline study

Reason / purpose for cross-reference:

reference to same study

Qualifier:

according to guideline

Guideline:

EU Method A.1 (Melting / Freezing Temperature)

Version / remarks:

18 march 2002

Deviations:

no

Qualifier:

according to guideline

Guideline:

OECD Guideline 102 (Melting point / Melting Range)

Version / remarks:

27th July 1995

Deviations:

no

GLP compliance:

no

Type of method:

differential scanning calorimetry

Remarks:

DSC

Melting / freezing pt.:

< -70 °C

Atm. press.:

101 325 Pa

Remarks on result:

other: There is a small melting point at 10-11°C, probably due to impurities.

TEPA: no crystallization / vitrification visible in this environment (closed Al cup, N2 atmosphere) and on this timescale. This does not exclude that in other conditions, such as prolonged storage time and contact with surfaces that may induce crystal seeding, solidification may take place. There is a small melting point at 10-11 °C.

 

Note:

Reports of solidification of the test substance above -20 °C is most likely due to reaction of TEPA with atmospheric CO₂, yielding a carbamate.

 

Conclusions:

The freezing point of the substance is below -70 °C.

Reference 3

Endpoint:

melting point/freezing point

Type of information:

experimental study

Adequacy of study:

supporting study

Reliability:

4 (not assignable)

Rationale for reliability incl. deficiencies:

other: handbook value, no details on determination method

Melting / freezing pt.:

ca. -40 °C

Relevancy 100%

Conclusions:

According to this handbook the melting point is -40° C

Description of key information

The freezing point of the substance is below -70 °C.

Key value for chemical safety assessment

Melting / freezing point at 101 325 Pa:

-71 °C

Additional information

Hantink-de Rooij E.E., 2010, Determination of freezing point of Tetraethylenepentamine (TEPA), Research, Development & Innovation AkzoNobel Arnhem, TheNetherlands.

Pour point < -20 °C.

Fair report, according to OECD and EU guidelines, certificate of analysis in the report.

Hantink-de Rooij E.E., 2010, Determination of freezing point of Tetraethylenepentamine (TEPA) with DSC, Research, Development & Innovation AkzoNobel Arnhem, TheNetherlands.

TEPA: no crystallization / vitrification visible >-70 °C at a scan rate 1 °C/min, except for a small melting point at 10-11 °C, possibly due to impurities.

Fair report, according to OECD and EU guidelines, certificate of analysis in the report.

Note: Reports of solidification of TEPA above -20 °C is most likely due to reaction of TEPA with atmospheric CO₂, yielding a carbamate.