Registration Dossier

Data platform availability banner - registered substances factsheets

Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Toxicological information

Sensitisation data (human)

Currently viewing:

Administrative data

Endpoint:
sensitisation data (humans)
Type of information:
other: short review
Adequacy of study:
supporting study
Study period:
no data
Reliability:
4 (not assignable)
Rationale for reliability incl. deficiencies:
other: Short summary on sensitivity to TETA in Poland.

Data source

Reference
Reference Type:
publication
Title:
Dermatitis from triethylenetetramine in Poland
Author:
Rudzki, E.
Year:
1980
Bibliographic source:
Contact Dermatitis. Apr;6(3):235-6.

Materials and methods

Type of sensitisation studied:
skin
Study type:
study with volunteers
GLP compliance:
no

Test material

Constituent 1
Chemical structure
Reference substance name:
Amines, polyethylenepoly-, triethylenetetramine fraction
EC Number:
292-588-2
EC Name:
Amines, polyethylenepoly-, triethylenetetramine fraction
Cas Number:
90640-67-8
Molecular formula:
C6H18N4, C8H20N4
IUPAC Name:
Amines, polyethylenepoly-, triethylenetetramine fraction
Test material form:
liquid

Method

Type of population:
occupational
Route of administration:
dermal

Results and discussion

Results of examinations:
Results from patch tests from different publications resulted in 20 to 50% positive response.

Applicant's summary and conclusion

Conclusions:
Sensitivity to the test substance is frequent in epoxy resin workers in Poland.
Executive summary:

In Poland, ca. 20 -50% of the patients working with epoxy resins tested positive on patch testing with Amines, polyethylenepoly-, triethylenetetramine fraction.