Registration Dossier
Registration Dossier
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EC number: 219-371-7 | CAS number: 2425-79-8
Toxicity to microorganisms
Administrative data
Link to relevant study record(s)
Description of key information
The substance was reported to have low toxicity to microorganisms derived from activated sludge, with a 3-h IC50 value for growth inhibition of greater than 100 mg/L (nominal) in an OECD guideline study (Test No. 209).
Key value for chemical safety assessment
- EC50 for microorganisms:
- 100 mg/L
Additional information
The inhibitory concentration of the substance on the respiration of aerobic waste water bacteria was determined in a mixed population of activated sewage sludge (Bader, 1989). The test method followed the OECD Guidelines for Testing of Chemicals No. 209. 3,5-Dichlorophenol was used as the reference substance at concentrations of 3.2, 10, and 32 mg/L. In this study the oxygen consumption rates were measured after time of 3-hours at nominal concentrations of 1.0, 3.2, 10, 32, and 100.1 mg/L. The inhibitory concentration (IC50) (3-h contact time) for reference substance was 13 mg/L, while the IC50 value (3-h contact time) for the test substance was greater than 100 mg/L (nominal), suggesting that the substance is not toxic to microorganisms.
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