Registration Dossier
Registration Dossier
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EC number: 248-122-5 | CAS number: 26942-95-0
Long-term toxicity to aquatic invertebrates
Administrative data
Link to relevant study record(s)
Description of key information
No chronic effects on aquatic invertebrates up to the limit of water solubility, read across.
Key value for chemical safety assessment
Additional information
Data on the chronic toxicity of 1,2,3-propanetriyl triisooctadecanoate (CAS 26942-95-0) to aquatic invertebrates are not available. The assessment was therefore based on a study conducted with the structurally related substance Glycerides, C14-18 and C16-18 unsatd, mono-, di- and tri- (CAS 91052-28-7) as part of a read across approach, which is in accordance with Regulation (EC) No. 1907/2006, Annex XI, 1.5. Further justification is given within the overall summary chapter 6.1 and within the analogue justification section 13. The long-term toxicity of Glycerides, C14-18 and C16-18 unsatd., mono-, di- and tri- (CAS 91052-28-7) was tested in a study conducted according to OECD 211, under GLP conditions. Daphnia magna were exposed to the substance at a single loading rate of 10 mg/L (limit test) for 21 days within a semi-static water regime. At the end of the exposure period, no effects on survival, reproduction or any other adverse effects were reported. Therefore the NOELR (21 d) was determined to be ≥ 10 mg/L (nominal, loading rate). Based on these results from a structurally related source substance (in accordance with Regulation (EC) No 1907/2006 Annex XI, 1.5) which is characterized by a similar ecotoxicological profile, chronic toxicological effects on aquatic invertebrates are not expected up to the limit of water solubility for 1,2,3-propanetriyl triisooctadecanoate (CAS 26942-95-0).
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