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EC number: 202-525-2 | CAS number: 96-69-5
Short-term toxicity to aquatic invertebrates
Administrative data
Link to relevant study record(s)
Description of key information
A 48-h static exposure of Daphnia magna resulted in an EC50 value of 0.16 mg/L (Monsanto, 1982, ES-82-SS-34). The organisms were exposed to Santonox R, according to a test protocol which was similar to OECD 202 guideline, and mobility was observed. Deviations from the OECD guideline regarding the number of replicates and the hardness are not assumed to significantly influence the results.
Key value for chemical safety assessment
Fresh water invertebrates
Fresh water invertebrates
- Effect concentration:
- 0.16 mg/L
Additional information
Of the four available and relevant studies, two used Daphnia magna as test species and two performed tests with different species of midge. Except for the study with the midge Chironomus tentans, all studies were found reliable. The study from which the key value for this endpoint was derived monitored mobility and provided an EC50, whereas the other studies reported concentrations at which 50 % of the organisms died (LC50s). The 48-h LC50s for Daphnia magna and for Chironomus tentans were in the same order of magnitute, i.e. 0.7 mg/L and >0.32 mg/L, respectively. The 48-h LC50 for Paratanytarsus parthenogenetica, on the other hand, was > 1000 mg/L. The selection of the key value for this endpoint is thus quite apparent.
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