Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
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EC number: 203-398-6 | CAS number: 106-44-5
Additional toxicological data
Administrative data
- Endpoint:
- additional toxicological information
- Type of information:
- experimental study
- Adequacy of study:
- other information
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: in vitro investigation, reliablility of limited relevance
Data source
Referenceopen allclose all
- Reference Type:
- publication
- Title:
- An evaluation of the utility of four in vitro short term tests for predicting the cytotoxicity of individual compounds derived from tobacco smoke
- Author:
- Curvall M et al.,
- Year:
- 1 984
- Bibliographic source:
- Cell Biol Toxicol 1, 173-193 (1984)
- Reference Type:
- publication
- Title:
- Effects of tobacco smoke compounds on the cilliary activity of the embryo chicken trachea in vitro. Toxicology 23, 41-55
- Author:
- Pettersson B et al.,
- Year:
- 1 982
- Bibliographic source:
- Toxicology 23, 41-55 (1982)
Materials and methods
- Type of study / information:
- Type: other: in vitro
Test material
- Reference substance name:
- p-cresol
- EC Number:
- 203-398-6
- EC Name:
- p-cresol
- Cas Number:
- 106-44-5
- Molecular formula:
- C7H8O
- IUPAC Name:
- p-cresol
- Details on test material:
- migrated dataset
Constituent 1
Results and discussion
Applicant's summary and conclusion
- Executive summary:
Ciliostasis within 15 min was observed when 5mM p-cresol was added to embryo chicken trachea in culture.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
