Dichloromethylbenzene

Other distribution data

Administrative data

Endpoint:

other distribution data

Type of information:

(Q)SAR

Adequacy of study:

other information

Study period:

2009

Reliability:

4 (not assignable)

Rationale for reliability incl. deficiencies:

results derived from a (Q)SAR model, with limited documentation / justification

Justification for type of information:

The substance described in this dossier is an isomeric mixture of five position isomers of dichlorotoluene. The similarities concerning chemical structure and key intrinsic properties such as log Kow and water solubility lead to the assumption that the values for ecotoxicological endpoints will also be very similar for the individual isomers and the mixture of isomers and that therefore results obtained with isomers can be useful for the assessment of the mixture.

Data source

Reference

Reference 1

Reference Type:

other company data

Title:

Unnamed

Year:

2009

Reference 2

Reference Type:

other company data

Title:

Unnamed

Year:

2010

Report date:

2010

Materials and methods

Test guideline

Qualifier:

no guideline followed

Principles of method if other than guideline:

The half life for the volatilisation of dichlorotoluene from water was calculated from two models of EPIWIN v.3.2: the Model River and the Model Lake.

GLP compliance:

no

Type of study:

other: calculation

Media:

water - air

Test material

Test material information

Constituent 1

Reference substance name:

Automatically generated during migration to IUCLID 6, no data available

IUPAC Name:

Automatically generated during migration to IUCLID 6, no data available

Details on test material:

- Name of test material (as cited in study report): since the test material is a mixture of isomers, the half lives were calculated individually for each isomer: 2,4-dichlorotoluene; 2,5-dichlorotoluene; 2,3-dichlorotoluene and 3,4-dichlorotoluene, 2,6 - dichlorotoluene.

Results and discussion

Any other information on results incl. tables

2,4/2,5/2,3/2,6 - DCT                  3,4 - DCT

Half-life from Model River:       1.5 h                                               1.6 h

Half-life from Model Lake:       122.5 h / 5.1 d                            123.7 h / 5.2d

Applicant's summary and conclusion

Executive summary:

The half lives for the volatilisation from water were calculated with EPIWIN v.3.2 for 2,4 - , 2,5 - 2,3, and 2,6 - dichlorotoluene from their Henry´s Law Constants (estimated by Group SAR method) to be 1.5 hours (Model River) and 5.1 d (Model Lake) and for 3,4 -dichloromethylbenzene from the Henry´s experimental database to be 1.6 hours (Model River) and 5.2 d (Model Lake).

Reference: Lanxess, 2009