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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Link to relevant study record(s)

Description of key information

Single Oral administration:

elimination in the foeces: 95 % of dose by 36 h

urinary elimination: < 0.1 %

bile elimination: 1 % in 24 h

IV administration

elimination in the foeces: 27 % of dose by 36 h; 71 % of dose by 96 h

urinary elimination: < 0.1 %

Key value for chemical safety assessment

Bioaccumulation potential:
low bioaccumulation potential

Additional information

There are no data about the basic toxicokinetics of AP 1300 S, thus the available information about the structural analogous Similar Substance 01 (CAS 21850-44-2, 1,1'-propane-2,2-diylbis[3,5-dibromo-4-(2,3-dibromopropoxy)benzene]) have been taken into account.


Similar Substance 01 shares with AP 1300 S the same structure, except for the fact that Similar Substance 01 presents two dibromobutane functional groups linked to the dibromophenol core, instead the dibromo-methylbutane as in the case of AP 1300 S. The justification for the Read Across approach has been detailed in the document attached to the IUCLID Section 13.