Registration Dossier
Registration Dossier
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EC number: 258-904-8 | CAS number: 53988-10-6
Hydrolysis
Administrative data
Link to relevant study record(s)
Description of key information
No abiotic degradation of the test item was observed. 1,3-Dihydro-4(or 5)-methyl-2H-benzimidazole-2-thione is found to be stable at 50°C at all three pH-values. Therefore it can be assumed that the test item is also stable at 25 °C and no half-life times and hydrolysis rates were calculated.
Key value for chemical safety assessment
Additional information
The hydrolysis behaviour of 1,3-dihydro-4(or 5)-methyl-2H-benzimidazole-2-thione were performed according to OECD Guidelines for Testing of Chemicals, Section 1 – Physical-Chemical Properties, OECD TG 111 (2004), Council Regulation (EC) No 440/2008, Guideline Part C – Methods for the Determination of Ecotoxicity, C.7. “Abiotic Degradation: Hydrolysis as a Function of pH” (adopted, May 2008). The tests were investigated at 50 °C at pH 4, pH 7 and pH 9 over a period of five day. The stability was monitored by HPLC analysis using UV-detection. No abiotic degradation of the test item was observed. 1,3-Dihydro-4(or 5)-methyl-2H-benzimidazole-2-thione is found to be stable at 50°C at all three pH-values. Therefore it can be assumed that the test item is also stable at 25 °C and no half-life times and hydrolysis rates were calculated.
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