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EC number: 258-904-8 | CAS number: 53988-10-6
Particle size distribution (Granulometry)
Administrative data
Link to relevant study record(s)
- Endpoint:
- particle size distribution (granulometry)
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 2021-12-20 - 2022-01-14
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- according to guideline
- Guideline:
- ISO 13320 (Particle size analysis - Laser diffraction methods)
- Version / remarks:
- 2020
- Qualifier:
- equivalent or similar to guideline
- Guideline:
- OECD Guideline 110 (Particle Size Distribution / Fibre Length and Diameter Distributions) - Method B: Fibre Length and Diameter Distributions
- Version / remarks:
- 1981
- GLP compliance:
- yes (incl. QA statement)
- Type of method:
- Laser scattering/diffraction
- Type of particle tested:
- primary particle
- Type of distribution:
- volumetric distribution
- Specific details on test material used for the study:
- batch number of test material: J210224B00
- Percentile:
- D10
- Mean:
- 0.7 µm
- St. dev.:
- 0.1
- Key result
- Percentile:
- D50
- Mean:
- 2 µm
- St. dev.:
- 0.1
- Percentile:
- D90
- Mean:
- 5.1 µm
- St. dev.:
- 0.1
- Conclusions:
- According to ISO 13320 (2020), OECD Test Guideline 110 (1981) and CIPAC Handbook K Test MT 187 the median particle size D50 of the test item 1,3-dihydro-4(or 5)-methyl-2H-benzimidazole-2-thione (non oil dispersed) was determined by laser diffraction measurement to be:
D50 = 2.0 µm - Executive summary:
In a guideline compliant GLP study according OECD TG 110 (1981) and ISO 13320 (2020) the particle size distribution of the substance 1,3-dihydro-4(or 5)-methyl-2H-benzimidazole-2-thione (non oil dispersed) was measured using laser diffraction. From the measured diffraction pattern the particle size distribution is calculated. From the cumulative distribution the characteristic values are derived. Two test series of 3 measurements each were performed with the test item. The calculation of the average was carried out with the original not rounded values.
Test series 1:
D10: 0.7 µm Standard deviation: < 0.1 µm
D50: 2.0 µm (Median diameter) Standard deviation: < 0.1 µm
D90: 5.0 µm Standard deviation: 0.3 µmTest series 2:
D10: 0.7 µm Standard deviation: < 0.1 µm
D50: 2.0 µm (Median diameter) Standard deviation: < 0.1 µm
D90: 5.1 µm Standard deviation: 0.2 µmAverage
D10: 0.7 µm Standard deviation: < 0.1 µm
D50: 2.0 µm (Median diameter) Standard deviation: < 0.1 µm
D90: 5.1 µm Standard deviation: < 0.1 µmAccording to ISO 13320 (2020), OECD Test Guideline 110 (1981) and CIPAC Handbook K Test MT 187 the median particle size D50 of the test item 1,3-dihydro-4(or 5)-methyl-2H-benzimidazole-2-thione (non oil dispersed) was determined by laser diffraction measurement to be:
D50 = 2.0 µm
- Endpoint:
- particle size distribution (granulometry)
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 2021-12-20 - 2022-01-14
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- according to guideline
- Guideline:
- ISO 13320 (Particle size analysis - Laser diffraction methods)
- Version / remarks:
- 2020
- Qualifier:
- equivalent or similar to guideline
- Guideline:
- OECD Guideline 110 (Particle Size Distribution / Fibre Length and Diameter Distributions) - Method B: Fibre Length and Diameter Distributions
- Version / remarks:
- 1981
- GLP compliance:
- yes (incl. QA statement)
- Type of method:
- Laser scattering/diffraction
- Type of particle tested:
- primary particle
- Type of distribution:
- volumetric distribution
- Specific details on test material used for the study:
- Batch No.: J201019B10
- Percentile:
- D10
- Mean:
- 1.4 µm
- St. dev.:
- 0.1
- Key result
- Percentile:
- D50
- Mean:
- 4.1 µm
- St. dev.:
- 0.1
- Percentile:
- D90
- Mean:
- 16.5 µm
- St. dev.:
- 0.1
- Conclusions:
- According to ISO 13320 (2020), OECD Test Guideline 110 (1981) and CIPAC Handbook K Test MT 187 the median particle size D50 of the test item 1,3-dihydro-4(or 5)-methyl-2H-benzimidazole-2-thione (oil dispersed) was determined by laser diffraction measurement to be:
D50 = 4.1 µm - Executive summary:
In a guideline compliant GLP study according OECD TG 110 (1981) and ISO 13320 (2020) the particle size distribution of the substance 1,3-dihydro-4(or 5)-methyl-2H-benzimidazole-2-thione (oil dispersed) was measured using laser diffraction. From the measured diffraction pattern the particle size distribution is calculated. From the cumulative distribution the characteristic values are derived. Two test series of 3 measurements each were performed with the test item. The calculation of the average was carried out with the original not rounded values.
Test series 1:
D10: 1.3 µm Standard deviation: 0.1 µm
D50: 4.1 µm (Median diameter) Standard deviation: 0.1 µm
D90: 16.4µm Standard deviation: 0.3 µmTest series 2:
D10: 1.4 µm Standard deviation: < 0.1 µm
D50: 4.0 µm (Median diameter) Standard deviation: 0.1 µm
D90: 16.6 µm Standard deviation: 0.2 µmAverage
D10: 1.4 µm Standard deviation: < 0.1 µm
D50: 4.1 µm (Median diameter) Standard deviation: < 0.1 µm
D90: 16.5 µm Standard deviation: 0.1 µmAccording to ISO 13320 (2020), OECD Test Guideline 110 (1981) and CIPAC Handbook K Test MT 187 the median particle size D50 of the test item 1,3-dihydro-4(or 5)-methyl-2H-benzimidazole-2-thione (oil dispersed) was determined by laser diffraction measurement to be:
D50 = 4.1 µm
Referenceopen allclose all
Test series 1:
D10: 0.7 µm Standard deviation: < 0.1 µm
D50: 2.0 µm (Median diameter) Standard deviation: < 0.1 µm
D90: 5.0 µm Standard deviation: 0.3 µm
Test series 2:
D10: 0.7 µm Standard deviation: < 0.1 µm
D50: 2.0 µm (Median diameter) Standard deviation: < 0.1 µm
D90: 5.1 µm Standard deviation: 0.2 µm
Test series 1:
D10: 1.3 µm Standard deviation: 0.1 µm
D50: 4.1 µm (Median diameter) Standard deviation: 0.1 µm
D90: 16.4 µm Standard deviation: 0.3 µm
Test series 2:
D10: 1.4 µm Standard deviation: < 0.1 µm
D50: 4.0 µm (Median diameter) Standard deviation: 0.1 µm
D90: 16.6 µm Standard deviation: 0.2 µm
Description of key information
According to ISO 13320 (2020), OECD Test Guideline 110 (1981) and CIPAC Handbook K Test MT 187 the median particle size D50 of the test item 1,3-dihydro-4(or 5)-methyl-2H-benzimidazole-2-thione (non oil dispersed) was determined by laser diffraction measurement to be:
D50 = 2.0 µm
According to ISO 13320 (2020), OECD Test Guideline 110 (1981) and CIPAC Handbook K Test MT 187 the median particle size D50 of the test item 1,3-dihydro-4(or 5)-methyl-2H-benzimidazole-2-thione (oil dispersed) was determined by laser diffraction measurement to be:
D50 = 4.1 µm
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