Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Hazard for aquatic organisms

Freshwater

Hazard assessment conclusion:
PNEC aqua (freshwater)
PNEC value:
0.002 mg/L
Assessment factor:
10
Extrapolation method:
assessment factor

Marine water

Hazard assessment conclusion:
PNEC aqua (marine water)
PNEC value:
0 mg/L
Assessment factor:
100
Extrapolation method:
assessment factor

STP

Hazard assessment conclusion:
PNEC STP
PNEC value:
100 mg/L
Assessment factor:
10
Extrapolation method:
assessment factor

Sediment (freshwater)

Hazard assessment conclusion:
PNEC sediment (freshwater)
PNEC value:
2.38 mg/kg sediment dw
Assessment factor:
1
Extrapolation method:
equilibrium partitioning method

Sediment (marine water)

Hazard assessment conclusion:
PNEC sediment (marine water)
PNEC value:
0.238 mg/kg sediment dw
Assessment factor:
1
Extrapolation method:
equilibrium partitioning method

Hazard for air

Air

Hazard assessment conclusion:
no hazard identified

Hazard for terrestrial organisms

Soil

Hazard assessment conclusion:
PNEC soil
PNEC value:
0.474 mg/kg soil dw
Extrapolation method:
equilibrium partitioning method

Hazard for predators

Secondary poisoning

Hazard assessment conclusion:
PNEC oral
PNEC value:
0.53 mg/kg food
Assessment factor:
90

Additional information

Conclusion on classification

According to the EU Classification, Labelling and Packaging of Substances and Mixtures (CLP) Regulation (EC) No. 1272/2008 the substance is not classified as an Acute Category 1. No acute toxicity was observed for the three trophic levels in three saturated solution limit tests thereby indicating that the substance is not classified for acute aquatic effects.


According to the EU Classification, Labelling and Packaging of Substances and Mixtures (CLP) Regulation (EC) No. 1272/2008 the substance is classified Aquatic chronic 1 (M factor=1) for long-term aquatic toxicity based on:


- Tested substance (6:2 FTA, EC No.:241-527-8) is not readily biodegradable (OECD 301C);


- Lowest NOEC value of 0.0157 mg/L (6:2 FTA, EC No.:241-527-8) based on read-across chronic study on fish (OECD 234) with 6:2 FTOH (EC No.:211-477-1; Goodband, 2021).


Given the rapid conversion of the test substance to 6:2 FTOH (EC No.:211-477-1) the latter is the more relevant substance to study for long-term effects. Therefore, the 122-d fish sexual development test (OECD 234; Goodband, 2021) and 21-day daphnid reproduction tests (OECD 211; DuPont Haskell Global Centers for Health & Environmental Sciences, 2013) studies for 6:2 FTOH (EC No.:211-477-1) were considered for the chronic classification.


According to the EU Classification, Labelling and Packaging of Substances and Mixtures (CLP) Regulation (EC) No. 1272/2008 the test substance is not hazardous to the ozone layer. There are no indications that global warming, ozone depletion in the stratosphere, ozone formation in the troposphere or acidification effects will occur based on the substance structure.