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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Ecotoxicological information

Short-term toxicity to fish

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Administrative data

Link to relevant study record(s)

Description of key information

With high probability acutely not harmful to fish.

Key value for chemical safety assessment

Fresh water fish

Fresh water fish
Effect concentration:
105 mg/L

Additional information

The effect of monoethanolamine on several fish species including rainbow trout (Oncorhynchus mykiss), fathead minnow (Pimephales promelas), goldfish (Carassius auratus), common carp (Cyprinus carpio), and medaka (Oryzias latipes) has been investigated. Test concentrations were analytically verified in most studies (PTAC, 2006; Huels, 1997, NITE, 1997; Geiger, 1990, Bridie, 1979). With the exception of very high concentrations (>1000 mg/L), the measured concentrations were within acceptable limits (±20% of nominal).

The LC50 values for 96-hour exposure range from > 100 mg/L for medaka to 2070 mg/l for fathead minnow. Studies in which the pH was measured indicate that the test material increased pH to approximately 10.1 – 10.2 in some studies. Studies performed in goldfish show that the LC50 value of monoethanolamine increases dramatically if the pH is neutralized, suggesting that the studies with lower LC50 values may have been influenced by high pH.

The lowest effect value was determined in a guideline study (Environment Canada EPS 1/RM/9, 1990/1996) with Oncorhynchus mykiss as test species. The fish were exposed to a series of 5 test concentrations and a control in a static approach. The 96 -h LC50 was 105 mg/L (nominal, analytically verified). The test solutions were not pH adjusted (PTAC, 2006).

It can be concluded that 2 -aminoethanol is with high probability not acutely harmful to fish.