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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Toxicological information

Carcinogenicity

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Administrative data

Description of key information

The available and relevant studies do not indicate that triethoxy(vinyl)silane (CAS 78-08-0) does fulfil the criteria for classification as germ cell mutagen or that it is able to induce hyperplasia and/or pre-neoplastic lesions at exposure concentrations relevant for each life cycle stage. Therefore, the conditions for a carcinogenicity study to be proposed or required set out in Column 2 of Annex X, 8.9.1, are not met. Thus, a carcinogenicity study is scientifically unjustified, will not be proposed and shall be omitted for reasons of animal welfare in accordance with Annex XI, 1.2, of Regulation (EC) 1907/2006.

Key value for chemical safety assessment

Carcinogenicity: via oral route

Endpoint conclusion
Endpoint conclusion:
no study available

Carcinogenicity: via inhalation route

Endpoint conclusion
Endpoint conclusion:
no study available

Carcinogenicity: via dermal route

Endpoint conclusion
Endpoint conclusion:
no study available

Justification for classification or non-classification

Based on expert judgement, a testing proposal for a carcinogenicity study with triethoxy(vinyl)silane (CAS 78-08-0) would be scientifically unjustified. The conclusion with regard to classification and labelling is "data lacking".

Additional information