Registration Dossier
Registration Dossier
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EC number: 700-954-4 | CAS number: 1338-23-4
Carcinogenicity
Administrative data
Description of key information
No carcinogenicity study is available for methyl-ethylketone peroxide.
In accordance with column 2 of REACH Annex X, a carcinogenicity study (required in section 8.9.1) does not need to be conducted as methyl-ethylketone peroxide did not reveal indication for mutagenic/genotoxic effects in a complete battery of in vitro and in some in vivo mutagenicity tests. In addition, there is no evidence from the repeated dose studies that the substance is able to induce hyperplasia and /or pre-neoplastic lesions.
Key value for chemical safety assessment
Carcinogenicity: via oral route
Endpoint conclusion
- Endpoint conclusion:
- no study available
Carcinogenicity: via inhalation route
Endpoint conclusion
- Endpoint conclusion:
- no study available
Carcinogenicity: via dermal route
Endpoint conclusion
- Endpoint conclusion:
- no study available
Justification for classification or non-classification
Classification, Labelling, and Packaging Regulation (EC) No 1272/2008
The available experimental test data are reliable and suitable for classification purposes under Regulation (EC) No 1272/2008. Based on available data the test item does not require classification as carcinogenic according to Regulation (EC) No 1272/2008 (CLP), as amended for the seventeenth time in Regulation (EU) No 2021/849.
Additional information
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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