Registration Dossier
Registration Dossier
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EC number: 201-245-8 | CAS number: 80-05-7
Exposure related observations in humans: other data
Administrative data
- Endpoint:
- exposure-related observations in humans: other data
- Type of information:
- experimental study
- Adequacy of study:
- other information
Data source
Reference
- Reference Type:
- publication
- Title:
- Fetal exposure to endocrine disruptors in Japanese pregnant women.
- Author:
- Hirahara F, Sumiyoshi Y, Yamanaka M, Sugawara T, Ishikawa H, Endoh M, Andoh N, Takahashi T & Mori C
- Year:
- 2 002
- Bibliographic source:
- Congenital Anomalies Kyoto. 42: 257.
Materials and methods
Test guideline
- Qualifier:
- no guideline followed
- Principles of method if other than guideline:
- Blood samples were obtained from pregnant women during the first, second and third trimesters and umbilical cord blood samples were drawn during their deliveries. Immunoreactive BPA was measured by ELISA. (As discussed in the abstract)
Test material
- Reference substance name:
- 4,4'-isopropylidenediphenol
- EC Number:
- 201-245-8
- EC Name:
- 4,4'-isopropylidenediphenol
- Cas Number:
- 80-05-7
- Molecular formula:
- C15H16O2
- IUPAC Name:
- 4-[2-(4-hydroxyphenyl)propan-2-yl]phenol
Constituent 1
Results and discussion
- Results:
- In maternal blood, the mean BPA level was 0.290 ng/ml; in the umbilical cord samples, the mean BPA level was 1.476 ng/ml. (As discussed in the abstract)
Applicant's summary and conclusion
- Executive summary:
Blood samples were obtained from pregnant women during the first, second and third trimesters and umbilical cord blood samples were drawn during their deliveries. Immunoreactive BPA was measured by ELISA. In maternal blood, the mean BPA level was 0.290 ng/ml; in the umbilical cord samples, the mean BPA level was 1.476 ng/ml. (As discussed in the abstract)
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